Survival and specific outcome of sickle cell disease patients after renal transplantation.
Adult
Anemia, Sickle Cell
/ complications
Case-Control Studies
Female
Follow-Up Studies
France
/ epidemiology
Graft Survival
Humans
Kaplan-Meier Estimate
Kidney Failure, Chronic
/ etiology
Kidney Transplantation
/ adverse effects
Male
Middle Aged
Opportunistic Infections
/ mortality
Postoperative Complications
/ mortality
Retrospective Studies
infections
patient survival
renal transplantation
sickle cell disease
Journal
British journal of haematology
ISSN: 1365-2141
Titre abrégé: Br J Haematol
Pays: England
ID NLM: 0372544
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
22
03
2019
accepted:
03
06
2019
pubmed:
28
7
2019
medline:
23
6
2020
entrez:
27
7
2019
Statut:
ppublish
Résumé
The prognosis of sickle cell disease (SCD) patients who need dialysis is poor, but experience with kidney transplantation is limited. This study assessed the characteristics of 36 SCD patients undergoing renal transplantation. Immediate post-surgical complications occurred in 25% of cases. Cytomegalovirus and bacterial infections were frequently observed. Twelve patients died after a median follow-up period of 17·4 months. Overall patient survival was significantly lower in SCD than in the control group without significant difference for overall death-censored graft survival. Our data suggest that renal transplantation should be systematically considered in SCD patients with end-stage renal disease.
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
676-680Informations de copyright
© 2019 British Society for Haematology and John Wiley & Sons Ltd.
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