Interplay between intracellular loop 1 and helix VIII of the angiotensin II type 2 receptor controls its activation.

Angiotensin II / pharmacology Binding Sites / drug effects Dose-Response Relationship, Drug HEK293 Cells Helix-Loop-Helix Motifs / drug effects Humans Intracellular Membranes / chemistry Protein Structure, Secondary Protein Structure, Tertiary Receptor, Angiotensin, Type 2 / agonists
Angiotensin II Angiotensin II receptor Chimeric receptors GPCR Signaling

Journal

Biochemical pharmacology
ISSN: 1873-2968
Titre abrégé: Biochem Pharmacol
Pays: England
ID NLM: 0101032

Informations de publication

Date de publication:
10 2019
Historique:
received: 14 05 2019
accepted: 19 07 2019
pubmed: 28 7 2019
medline: 2 7 2020
entrez: 27 7 2019
Statut: ppublish

Résumé

The signaling mechanisms of the angiotensin II type 2 receptor (AT

Identifiants

DOI: 10.1016/j.bcp.2019.07.018 PMID: 31348898
pubmed: 31348898
pii: S0006-2952(19)30273-4
doi: 10.1016/j.bcp.2019.07.018
pii:
doi:

Substances chimiques

Receptor, Angiotensin, Type 2 0
Angiotensin II 11128-99-7

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

330-338

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Alexandre Connolly (A)

Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada.

Brian J Holleran (BJ)

Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada.

Élie Simard (É)

Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada.

Jean-Patrice Baillargeon (JP)

Division of Endocrinology, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke J1H 5N4, Québec, Canada.

Pierre Lavigne (P)

Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada; Department of Biochemistry, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada.

Richard Leduc (R)

Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada. Electronic address: Richard.Leduc@USherbrooke.ca.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Angiotensines › Angiotensine-II › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Éléments structuraux des protéines › Motifs à hélice-boucle-hélice › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Membranes intracellulaires › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Interplay between intracellular loop 1 and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteurs aux angiotensines › Récepteur de type 2 à l'angiotensine-II › Interplay between intracellular loop 1 and...