A Probable Fatal Case of Oleander (Nerium oleander) Poisoning on a Cattle Farm: A New Method of Detection and Quantification of the Oleandrin Toxin in Rumen.
LC–HRMS
Nerium oleander
cattle
oleander
poisonous plant
Journal
Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765
Informations de publication
Date de publication:
25 07 2019
25 07 2019
Historique:
received:
07
06
2019
revised:
01
07
2019
accepted:
21
07
2019
entrez:
28
7
2019
pubmed:
28
7
2019
medline:
22
9
2020
Statut:
epublish
Résumé
Oleander (Nerium oleander) is an ornamental plant common in tropical and sub-tropical regions that is becoming increasingly widespread, even in temperate regions. Oleander poisoning may occur in animals and humans. The main active components contained in the plant are cardiac glycosides belonging to the class of cardenolides that are toxic to many species, from human to insects. This work describes a case of oleander poisoning that occurred on a small cattle farm and resulted in the fatality of all six resident animals. Furthermore, the investigation of the poisonous agent is described, with particular focus on the characterization of the oleandrin toxin that was recovered from the forage and rumen contents. The innovation of this study is the first description of the detection and quantification of the oleandrin toxin by liquid chromatography-high resolution mass spectrometry (LC-HRMS) in rumen.
Identifiants
pubmed: 31349685
pii: toxins11080442
doi: 10.3390/toxins11080442
pmc: PMC6723884
pii:
doi:
Substances chimiques
Cardenolides
0
oleandrin
II95UDU7I4
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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