Castleman Disease.
Castleman disease
Human herpes virus type 8
Lymphoproliferative disorder
Multicentric Castleman disease
Unicentric hyaline-vascular Castleman disease
Journal
Surgical pathology clinics
ISSN: 1875-9157
Titre abrégé: Surg Pathol Clin
Pays: United States
ID NLM: 101491209
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
entrez:
30
7
2019
pubmed:
30
7
2019
medline:
28
1
2020
Statut:
ppublish
Résumé
Castleman disease (CD) is divided clinically into unicentric or multicentric type. Pathologically, CD is divided into hyaline-vascular and plasma cell variants. Unicentric CD is most common, about 75% of these cases are hyaline-vascular variant, and surgical excision is often curative. In contrast, there are a number of types of multicentric CD including HHV8-associated, idiopathic, and a subset of cases that arise in association with POEMS syndrome. Therapy is required for most patients with multicentric CD, but there is no consensus approach currently. As is evidence, the designation Castleman disease encompasses a heterogeneous group of diseases of varied pathogenesis and which require different therapies.
Identifiants
pubmed: 31352991
pii: S1875-9181(19)30020-0
doi: 10.1016/j.path.2019.03.003
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
849-863Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.