Sleep debt: the impact of weekday sleep deprivation on cardiovascular health in older women.


Journal

Sleep
ISSN: 1550-9109
Titre abrégé: Sleep
Pays: United States
ID NLM: 7809084

Informations de publication

Date de publication:
09 10 2019
Historique:
received: 20 12 2018
revised: 10 05 2019
pubmed: 31 7 2019
medline: 6 5 2020
entrez: 31 7 2019
Statut: ppublish

Résumé

Short sleep duration is associated with increased cardiovascular disease (CVD) risk. However, it is uncertain whether sleep debt, a measure of sleep deficiency during the week compared to the weekend, confers increased cardiovascular risk. Because sleep disturbances increase with age particularly in women, we examined the relationship between sleep debt and ideal cardiovascular health (ICH) in older women. Sleep debt is defined as the difference between self-reported total weekday and weekend sleep hours of at least 2 hours among women without apparent CVD and cancer participating in the Women's Health Stress Study follow-up cohort of female health professionals (N = 22 082). The ICH consisted of seven health factors and behaviors as defined by the American Heart Association Strategic 2020 goals including body mass index, smoking, physical activity, diet, blood pressure, total cholesterol, and glucose. Mean age was 72.1 ± 6.0 years. Compared to women with no sleep debt, women with sleep debt were more likely to be obese and have hypertension (pall < .05). Linear regression models adjusted for age and race/ethnicity revealed that sleep debt was significantly associated with poorer ICH (B = -0.13 [95% CI = -0.18 to -0.08]). The relationship was attenuated but remained significant after adjustment for education, income, depression/anxiety, cumulative stress, and snoring. Sleep debt was associated with poorer ICH, despite taking into account socioeconomic status and psychosocial factors. These results suggest that weekly sleep duration variation, possibly leading to circadian misalignment, may be associated with cardiovascular risk in older women.

Identifiants

pubmed: 31361895
pii: 5541558
doi: 10.1093/sleep/zsz149
pmc: PMC6783901
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NHLBI NIH HHS
ID : R35 HL135818
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG038492
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA182913
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL142051
Pays : United States

Informations de copyright

© Sleep Research Society 2019. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

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Auteurs

Tomás Cabeza de Baca (T)

Department of Psychology, School of Mind, Brain, and Behavior, University of Arizona, Tucson, AZ.

Koharu Loulou Chayama (KL)

British Columbia Centre on Substance Use, Providence Health Care, Vancouver, British Columbia, Canada.

Susan Redline (S)

Harvard Medical School, Brigham and Women's Hospital, Boston, MA.
Beth Israel Deaconess Medical Center, Boston, MA.

Natalie Slopen (N)

Department of Epidemiology and Biostatistics, University of Maryland College Park, School of Public Health, College Park, MD.

Fumika Matsushita (F)

Division of Cardiology, Department of Medicine, University of California, San Francisco, CA.

Aric A Prather (AA)

Department of Psychiatry, University of California, San Francisco, CA.

David R Williams (DR)

Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA.
Department of African and African American Studies, Harvard University, Cambridge, MA.

Julie E Buring (JE)

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

Alan M Zaslavsky (AM)

Department of Health Care Policy, Harvard Medical School, Boston, MA.

Michelle A Albert (MA)

Division of Cardiology, Department of Medicine, University of California, San Francisco, CA.

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