Post-exercise carbohydrate and energy availability induce independent effects on skeletal muscle cell signalling and bone turnover: implications for training adaptation.
Adaptation, Physiological
/ physiology
Adult
Bone Remodeling
/ physiology
Carbohydrates
/ physiology
Energy Metabolism
/ physiology
Exercise
/ physiology
Glycogen
/ metabolism
Humans
Lipid Metabolism
/ physiology
Male
Muscle, Skeletal
/ metabolism
Organelle Biogenesis
Physical Endurance
/ physiology
Signal Transduction
/ physiology
Young Adult
p38 Mitogen-Activated Protein Kinases
/ metabolism
IL-6
PGC-1α
caloric restriction
βCTX
Journal
The Journal of physiology
ISSN: 1469-7793
Titre abrégé: J Physiol
Pays: England
ID NLM: 0266262
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
received:
26
04
2019
accepted:
30
07
2019
pubmed:
1
8
2019
medline:
15
8
2020
entrez:
1
8
2019
Statut:
ppublish
Résumé
Reduced carbohydrate (CHO) availability before and after exercise may augment endurance training-induced adaptations of human skeletal muscle, as mediated via modulation of cell signalling pathways. However, it is not known whether such responses are mediated by CHO restriction, energy restriction or a combination of both. In recovery from a twice per day training protocol where muscle glycogen concentration is maintained within 200-350 mmol kg We examined the effects of post-exercise carbohydrate (CHO) and energy availability (EA) on potent skeletal muscle cell signalling pathways (regulating mitochondrial biogenesis and lipid metabolism) and indicators of bone metabolism. In a repeated measures design, nine males completed a morning (AM) and afternoon (PM) high-intensity interval (HIT) (8 × 5 min at 85%
Substances chimiques
Carbohydrates
0
Glycogen
9005-79-2
p38 Mitogen-Activated Protein Kinases
EC 2.7.11.24
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4779-4796Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
© 2019 The Authors. The Journal of Physiology © 2019 The Physiological Society.
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