Presystolic Wave is Associated with Subclinical Left Ventricular Dysfunction Assessed by Myocardial Performance Index in Type 2 Diabetes Mellitus.
Adult
Aged
Body Mass Index
Cross-Sectional Studies
Diabetes Mellitus, Type 2
/ physiopathology
Echocardiography, Doppler
/ methods
Female
Heart
/ diagnostic imaging
Humans
Male
Middle Aged
Reference Values
Risk Factors
Statistics, Nonparametric
Stroke Volume
/ physiology
Ventricular Dysfunction, Left
/ diagnostic imaging
Ventricular Function, Left
/ physiology
Journal
Arquivos brasileiros de cardiologia
ISSN: 1678-4170
Titre abrégé: Arq Bras Cardiol
Pays: Brazil
ID NLM: 0421031
Informations de publication
Date de publication:
29 07 2019
29 07 2019
Historique:
received:
12
07
2018
accepted:
14
11
2018
pubmed:
1
8
2019
medline:
11
3
2020
entrez:
1
8
2019
Statut:
epublish
Résumé
Myocardial performance index (MPI), demonstrates both systolic and diastolic functions of the left ventricle. Presystolic wave (PSW) is frequently detected on Doppler examination of the left ventricular outflow tract and possible mechanism of PSW is impaired LV compliance and left ventricular stiffness. To investigate the relationship between PSW and MPI in type 2 diabetic patients. A total of 129 type 2 diabetic patients were included in this study. Patients were divided into two groups according to the presence of PSW on Doppler echocardiography. There were 90 patients (38 male, mean age 57.77 ± 10.91 years) in the PSW-positive group and 39 patients (13 male; mean age: 55.31 ± 11.29 years) in the PSW-negative group. The p values of < 0.05 were considered statistically significant. MPI was higher in PSW- positive group (0.63 ± 0.17vs 0.52 ± 0.13, p < 0.001). In addition, subclinical left ventricle dysfunction (LVD) was higher in the PSW- positive group (p = 0.029). Univariate analysis showed that the presence of PSW associated with abnormal MPI (p = 0.031). Pearson correlation analysis showed that PSW velocity correlated with MPI (r: 0.286, p = 0.006). Presence of the PSW on Doppler examination was associated with subclinical LV dysfunction in patients with DM type 2. This easy-to-perform echocardiographic parameter may be related to subclinical LVD among patients with type 2 DM.
Sections du résumé
BACKGROUND
Myocardial performance index (MPI), demonstrates both systolic and diastolic functions of the left ventricle. Presystolic wave (PSW) is frequently detected on Doppler examination of the left ventricular outflow tract and possible mechanism of PSW is impaired LV compliance and left ventricular stiffness.
OBJECTIVE
To investigate the relationship between PSW and MPI in type 2 diabetic patients.
METHOD
A total of 129 type 2 diabetic patients were included in this study. Patients were divided into two groups according to the presence of PSW on Doppler echocardiography. There were 90 patients (38 male, mean age 57.77 ± 10.91 years) in the PSW-positive group and 39 patients (13 male; mean age: 55.31 ± 11.29 years) in the PSW-negative group. The p values of < 0.05 were considered statistically significant.
RESULTS
MPI was higher in PSW- positive group (0.63 ± 0.17vs 0.52 ± 0.13, p < 0.001). In addition, subclinical left ventricle dysfunction (LVD) was higher in the PSW- positive group (p = 0.029). Univariate analysis showed that the presence of PSW associated with abnormal MPI (p = 0.031). Pearson correlation analysis showed that PSW velocity correlated with MPI (r: 0.286, p = 0.006).
CONCLUSION
Presence of the PSW on Doppler examination was associated with subclinical LV dysfunction in patients with DM type 2. This easy-to-perform echocardiographic parameter may be related to subclinical LVD among patients with type 2 DM.
Identifiants
pubmed: 31365600
pii: S0066-782X2019005001301
doi: 10.5935/abc.20190134
pmc: PMC6777877
pii:
doi:
Types de publication
Journal Article
Langues
eng
por
Sous-ensembles de citation
IM
Pagination
207-215Commentaires et corrections
Type : CommentIn
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