A New Approach in Cancer Treatment: Discovery of Chlorido[

Antineoplastic Agents / chemical synthesis Cell Proliferation / drug effects Coordination Complexes / chemical synthesis Dose-Response Relationship, Drug Drug Discovery Drug Screening Assays, Antitumor Ferric Compounds Ferroptosis / drug effects HL-60 Cells Humans Iron Compounds / chemical synthesis Leukemia / drug therapy Molecular Structure Neuroblastoma / drug therapy Phenylenediamines / chemical synthesis Reactive Oxygen Species / metabolism Structure-Activity Relationship Tumor Cells, Cultured

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
12 09 2019
Historique:
pubmed: 2 8 2019
medline: 1 7 2020
entrez: 2 8 2019
Statut: ppublish

Résumé

Chlorido[

Identifiants

DOI: 10.1021/acs.jmedchem.9b00814 PMID: 31369259
pubmed: 31369259
doi: 10.1021/acs.jmedchem.9b00814
doi:

Substances chimiques

Antineoplastic Agents 0
Coordination Complexes 0
Ferric Compounds 0
Iron Compounds 0
Phenylenediamines 0
Reactive Oxygen Species 0
chlorido(N,N'-disalicylidene-1,2-phenylenediamine)iron(III) 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8053-8061

Auteurs

Jessica Sagasser (J)

Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck , University of Innsbruck, CCB-Center for Chemistry and Biomedicine , Innrain 80-82 , 6020 Innsbruck , Austria.

Benjamin N Ma (BN)

Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck , University of Innsbruck, CCB-Center for Chemistry and Biomedicine , Innrain 80-82 , 6020 Innsbruck , Austria.

Daniel Baecker (D)

Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck , University of Innsbruck, CCB-Center for Chemistry and Biomedicine , Innrain 80-82 , 6020 Innsbruck , Austria.

Stefan Salcher (S)

Tyrolean Cancer Research Institute , Innrain 66 , 6020 Innsbruck , Austria.

Martin Hermann (M)

Department of Anesthesiology and Critical Care Medicine , Medical University Innsbruck , Anichstraße 35 , 6020 Innsbruck , Austria.

Julia Lamprecht (J)

Tyrolean Cancer Research Institute , Innrain 66 , 6020 Innsbruck , Austria.

Stefanie Angerer (S)

Tyrolean Cancer Research Institute , Innrain 66 , 6020 Innsbruck , Austria.
Immunobiology and Stem Cell Laboratory, Department of Internal Medicine V (Hematology and Oncology) , Medical University Innsbruck , Anichstraße 35 , 6020 Innsbruck , Austria.

Petra Obexer (P)

Tyrolean Cancer Research Institute , Innrain 66 , 6020 Innsbruck , Austria.
Department of Pediatrics II , Medical University Innsbruck , Innrain 66 , 6020 Innsbruck , Austria.

Brigitte Kircher (B)

Tyrolean Cancer Research Institute , Innrain 66 , 6020 Innsbruck , Austria.
Immunobiology and Stem Cell Laboratory, Department of Internal Medicine V (Hematology and Oncology) , Medical University Innsbruck , Anichstraße 35 , 6020 Innsbruck , Austria.

Ronald Gust (R)

Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck , University of Innsbruck, CCB-Center for Chemistry and Biomedicine , Innrain 80-82 , 6020 Innsbruck , Austria.
ORCID: 0000-0002-0427-4012

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Composés chimiques organiques › Complexes de coordination › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de criblage d'agents antitumoraux › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du fer › Composés du fer III › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Ferroptose › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Cellules HL-60 › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du fer › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Leucémies › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Tumeurs neuroectodermiques primitives › Tumeurs neuroectodermiques primitives périphériques › Neuroblastome › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Composés chimiques organiques › Amines › Polyamines › Diamines › Phénylènediamines › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › A New Approach in Cancer Treatment: Discovery...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › A New Approach in Cancer Treatment: Discovery...