Aortic arch replacement with frozen elephant trunk technique - a single-center study.


Journal

Journal of cardiothoracic surgery
ISSN: 1749-8090
Titre abrégé: J Cardiothorac Surg
Pays: England
ID NLM: 101265113

Informations de publication

Date de publication:
01 Aug 2019
Historique:
received: 03 05 2019
accepted: 22 07 2019
entrez: 3 8 2019
pubmed: 3 8 2019
medline: 27 11 2019
Statut: epublish

Résumé

The frozen elephant trunk (FET) technique was developed to facilitate the two-stage surgery of extensive pathologies of the thoracic aorta and is now routinely applied in acute and chronic aortic syndromes. From 11/2006 to 07/2017, 68 patients underwent aortic arch repair using the FET technique. Patients received either the Jotec E-vita Open graft (n = 57) or the Vascutek Thoraflex hybrid prosthesis (n = 11). Both, group 1 (acute aortic dissection type A and B; symptomatic penetrating aortic ulcer) and group 2 (aortic aneurysm; chronic aortic dissection) included 34 patients each. Early mortality was 13.2% (14.7% in group 1 vs. 11.7% in group 2, p = 0.720). Neurological complications occurred in 12 patients (17.6%) (stroke: 8.8 vs. 11.7%; p = 0.797 and spinal cord injury: 8.8 vs. 5.9%; p = 0.642 in groups 1 vs. 2 respectively). Cardiopulmonary bypass time and cross clamp time were significantly longer in group 1 (252.2 ± 73.5 and 148.3 ± 34 min vs. 189.2 ± 47.8 and 116.3 ± 34.5 min; p <  0.001). The overall 1-, 3- and 7-year-survival was 80.9, 80.9 and 74.2% with no significant differences between groups 1 and 2. Expansion of true lumen after FET implantation was significant at all levels in both groups for patients with aortic dissection. One-, 3-, and 7-year-freedom from secondary (re-)intervention for patients for aortic dissection was 96.9, 90.2 and 82.7% with no significant differences between groups 1 and 2; p = 0.575. The FET technique can be applied in acute aortic syndromes with similar risks regarding adverse events or mortality when compared to chronic degenerative aortic disease. Postoperative increase in true lumen diameter mirrors decrease of false lumen diameter, goes along with favorable midterm outcome and prolongs freedom from secondary interventions in acute aortic dissection.

Sections du résumé

BACKGROUND BACKGROUND
The frozen elephant trunk (FET) technique was developed to facilitate the two-stage surgery of extensive pathologies of the thoracic aorta and is now routinely applied in acute and chronic aortic syndromes.
METHODS METHODS
From 11/2006 to 07/2017, 68 patients underwent aortic arch repair using the FET technique. Patients received either the Jotec E-vita Open graft (n = 57) or the Vascutek Thoraflex hybrid prosthesis (n = 11). Both, group 1 (acute aortic dissection type A and B; symptomatic penetrating aortic ulcer) and group 2 (aortic aneurysm; chronic aortic dissection) included 34 patients each.
RESULTS RESULTS
Early mortality was 13.2% (14.7% in group 1 vs. 11.7% in group 2, p = 0.720). Neurological complications occurred in 12 patients (17.6%) (stroke: 8.8 vs. 11.7%; p = 0.797 and spinal cord injury: 8.8 vs. 5.9%; p = 0.642 in groups 1 vs. 2 respectively). Cardiopulmonary bypass time and cross clamp time were significantly longer in group 1 (252.2 ± 73.5 and 148.3 ± 34 min vs. 189.2 ± 47.8 and 116.3 ± 34.5 min; p <  0.001). The overall 1-, 3- and 7-year-survival was 80.9, 80.9 and 74.2% with no significant differences between groups 1 and 2. Expansion of true lumen after FET implantation was significant at all levels in both groups for patients with aortic dissection. One-, 3-, and 7-year-freedom from secondary (re-)intervention for patients for aortic dissection was 96.9, 90.2 and 82.7% with no significant differences between groups 1 and 2; p = 0.575.
CONCLUSION CONCLUSIONS
The FET technique can be applied in acute aortic syndromes with similar risks regarding adverse events or mortality when compared to chronic degenerative aortic disease. Postoperative increase in true lumen diameter mirrors decrease of false lumen diameter, goes along with favorable midterm outcome and prolongs freedom from secondary interventions in acute aortic dissection.

Identifiants

pubmed: 31370864
doi: 10.1186/s13019-019-0969-9
pii: 10.1186/s13019-019-0969-9
pmc: PMC6676558
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

147

Références

J Thorac Cardiovasc Surg. 2000 Mar;119(3):558-65
pubmed: 10694617
Am J Cardiol. 2000 Oct 15;86(8):868-72
pubmed: 11024403
Cardiovasc Surg. 2000 Dec;8(7):545-9
pubmed: 11068215
J Thorac Cardiovasc Surg. 2003 Jun;125(6):1550-3
pubmed: 12830086
Circulation. 2005 Aug 30;112(9 Suppl):I249-52
pubmed: 16159825
Ann Thorac Surg. 2009 Jan;87(1):103-8
pubmed: 19101279
Eur J Cardiothorac Surg. 2011 Oct;40(4):875-80
pubmed: 21382727
Eur J Cardiothorac Surg. 2011 Nov;40(5):1078-84
pubmed: 21570858
J Cardiovasc Surg (Torino). 2011 Oct;52(5):717-23
pubmed: 21894139
Ann Thorac Surg. 2011 Nov;92(5):1663-70; discussion 1670
pubmed: 22051263
J Vasc Surg. 2013 Apr;57(4 Suppl):11S-7S
pubmed: 23522712
Eur J Cardiothorac Surg. 2013 Nov;44(5):949-57
pubmed: 23660556
Eur J Cardiothorac Surg. 2013 Nov;44(5):e325-31
pubmed: 23918768
Ann Cardiothorac Surg. 2013 Sep;2(5):581-91
pubmed: 24109565
Ann Cardiothorac Surg. 2013 Sep;2(5):597-605
pubmed: 24109567
Ann Cardiothorac Surg. 2013 Sep;2(5):606-11
pubmed: 24109568
Ann Cardiothorac Surg. 2013 Sep;2(5):612-20
pubmed: 24109569
Lancet Neurol. 2014 May;13(5):490-502
pubmed: 24703207
Future Cardiol. 2015;11(1):39-43
pubmed: 25606701
Eur J Cardiothorac Surg. 2016 Jan;49(1):118-24
pubmed: 25669646
J Thorac Cardiovasc Surg. 2015 May;149(5):1286-93
pubmed: 25816956
PLoS One. 2015 Apr 22;10(4):e0124461
pubmed: 25902057
Eur J Cardiothorac Surg. 2017 Oct 1;52(4):733-739
pubmed: 28591766
Eur J Cardiothorac Surg. 2017 Nov 1;52(5):858-866
pubmed: 28977379
Eur J Cardiothorac Surg. 2018 Mar 1;53(3):525-530
pubmed: 28977457
Heart Lung Circ. 2019 Feb;28(2):213-222
pubmed: 30056013
J Thorac Cardiovasc Surg. 2019 Jan;157(1):1-2
pubmed: 30316549
J Thorac Cardiovasc Surg. 2019 Jul;158(1):27-34.e9
pubmed: 31248512
Circulation. 1996 Nov 1;94(9 Suppl):II188-93
pubmed: 8901744
J Thorac Cardiovasc Surg. 1996 Nov;112(5):1389-90
pubmed: 8911340

Auteurs

Jamila Kremer (J)

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Fabian Preisner (F)

Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld, 400, Heidelberg, Germany.

Bashar Dib (B)

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Ursula Tochtermann (U)

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Arjang Ruhparwar (A)

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Matthias Karck (M)

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Mina Farag (M)

Department of Cardiac Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. mina.farag@med.uni-heidelberg.de.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH