Combined zinc and vitamin B6 deficiency in a patient with diffuse red rash and angular cheilitis 6 years after Roux-en-Y gastric bypass.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
02 Aug 2019
Historique:
entrez: 5 8 2019
pubmed: 5 8 2019
medline: 30 1 2020
Statut: epublish

Résumé

A 39-year-old woman with a history of Roux-en-Y gastric bypass (RYGB) surgery and alcohol use presented with a confluent erythematous rash involving the perineum spreading outward to the abdomen, thighs and lower back. She had angular cheilitis and glossitis. The rash was painful and blistering in scattered areas. She was hypotensive and appeared to be in septic or hypovolemic shock at presentation. Serum levels of zinc and vitamin B6 were critically low and biopsy of her rash returned suggestive of a nutritional deficiency as its source. The rash slowly improved over the following 2 weeks with oral zinc and vitamin B6 replacement. The body rash resembled that of infants born with inherited defects in zinc transporters, referred to as acrodermatitis enteropathica (AE). This case may represent an acquired case of AE in the setting of prior RYGB.

Identifiants

pubmed: 31377720
pii: 12/8/e230605
doi: 10.1136/bcr-2019-230605
pmc: PMC6685412
pii:
doi:

Substances chimiques

Vitamin B 6 8059-24-3
Zinc J41CSQ7QDS

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Jared Freitas (J)

Department of Internal Medicine, School of Medicine, University of Florida, Gainesville, Florida, USA.

Patrick Bliven (P)

Department of Internal Medicine, School of Medicine, University of Florida, Gainesville, Florida, USA.

Robert Case (R)

Department of Internal Medicine, School of Medicine, University of Florida, Gainesville, Florida, USA.

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Classifications MeSH