Bariatric surgery before and after kidney transplantation: long-term weight loss and allograft outcomes.
Adult
Allografts
/ physiology
Bariatric Surgery
/ adverse effects
Body Mass Index
Female
Graft Survival
/ physiology
Humans
Kidney Transplantation
/ adverse effects
Male
Middle Aged
Obesity, Morbid
/ surgery
Postoperative Complications
/ epidemiology
Retrospective Studies
Time-to-Treatment
Weight Loss
/ physiology
Kidney transplantation
bariatric surgery
body mass index
obesity
weight gain
weight loss surgery
Journal
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
ISSN: 1878-7533
Titre abrégé: Surg Obes Relat Dis
Pays: United States
ID NLM: 101233161
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
03
06
2018
revised:
27
03
2019
accepted:
02
04
2019
entrez:
6
8
2019
pubmed:
6
8
2019
medline:
7
7
2020
Statut:
ppublish
Résumé
Severe obesity is frequently a barrier to kidney transplantation, and kidney transplant recipients often have significant weight gain following transplantation. The goals of this study were to evaluate the long-term risks and benefits of bariatric surgery before and after kidney transplantation. University Hospital, United States. We performed a retrospective cohort study of 43 patients who had pretransplantation bariatric surgery and 21 patients who had posttransplantation bariatric surgery from 1994 to 2017 with propensity-score matching to identify matched controls using national registry data. Body mass index at the time of transplantation was similar in patients who underwent bariatric surgery before versus after transplantation (32 versus 34 kg/m Bariatric surgery before and after kidney transplantation results in similar maintenance of weight loss and improved long-term allograft survival compared with matched controls. Bariatric surgery appears to be a safe and reasonable approach to weight loss both before and after transplantation.
Sections du résumé
BACKGROUND
BACKGROUND
Severe obesity is frequently a barrier to kidney transplantation, and kidney transplant recipients often have significant weight gain following transplantation.
OBJECTIVES
OBJECTIVE
The goals of this study were to evaluate the long-term risks and benefits of bariatric surgery before and after kidney transplantation.
SETTING
METHODS
University Hospital, United States.
METHODS
METHODS
We performed a retrospective cohort study of 43 patients who had pretransplantation bariatric surgery and 21 patients who had posttransplantation bariatric surgery from 1994 to 2017 with propensity-score matching to identify matched controls using national registry data.
RESULTS
RESULTS
Body mass index at the time of transplantation was similar in patients who underwent bariatric surgery before versus after transplantation (32 versus 34 kg/m
CONCLUSIONS
CONCLUSIONS
Bariatric surgery before and after kidney transplantation results in similar maintenance of weight loss and improved long-term allograft survival compared with matched controls. Bariatric surgery appears to be a safe and reasonable approach to weight loss both before and after transplantation.
Identifiants
pubmed: 31378281
pii: S1550-7289(19)30132-7
doi: 10.1016/j.soard.2019.04.002
pmc: PMC6690384
mid: NIHMS1045082
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
935-941Subventions
Organisme : NHLBI NIH HHS
ID : K23 HL133843
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.
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