In early pubertal boys, testosterone and LH are associated with improved anti-oxidation during an aerobic exercise bout.
Catalase
/ blood
Child
Cross-Sectional Studies
Exercise
/ physiology
Follicle Stimulating Hormone
/ blood
Glutathione
/ blood
Humans
Luteinizing Hormone
/ blood
Male
Oxidative Stress
/ physiology
Pediatric Obesity
/ blood
Puberty
/ blood
Testosterone
/ blood
Thiobarbituric Acid Reactive Substances
/ metabolism
HPT axis
LH, FSH, testosterone
obesity
puberty
Journal
Endocrine
ISSN: 1559-0100
Titre abrégé: Endocrine
Pays: United States
ID NLM: 9434444
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
19
04
2019
accepted:
26
07
2019
pubmed:
6
8
2019
medline:
28
5
2020
entrez:
6
8
2019
Statut:
ppublish
Résumé
To investigate the association of the hypothalamic-pituitary-testicular (HPT) axis with pro- and anti- oxidation, in relation to puberty and obesity in boys, before and after an aerobic exercise bout. This is a cross-sectional human observational study of 92 healthy normal-weight, obese pre- and early- pubertal boys that underwent a blood sampling, before, and after an aerobic exercise bout at 70% VO Baseline LH, FSH, and tT concentrations were greater in early, than in pre- pubertal boys, independently of weight status. Post-exercise, LH concentrations decreased in early pubertal boys while FSH concentrations did not change in any of the studied groups. Baseline and post-exercise tT concentrations were lower in obese than in normal-weight early pubertal boys, while baseline and post-exercise LH and FSH concentrations did not differ between these groups. Post-exercise tT concentrations increased in early pubertal obese boys. Baseline LH, FSH and tT concentrations correlated positively with baseline anti-oxidation markers concentrations in pre-pubertal boys. Baseline tT concentrations correlated positively with the increase of TAC concentrations in early pubertal normal-weight boys. In all boys, baseline LH concentrations were the best positive predictors for the exercise-associated increase of TAC concentrations. It appears that the HPT axis maturation during puberty (in particular its LH and testosterone components) is positively associated with the increase of anti-oxidation during a bout of aerobic exercise.
Identifiants
pubmed: 31378848
doi: 10.1007/s12020-019-02037-1
pii: 10.1007/s12020-019-02037-1
doi:
Substances chimiques
Thiobarbituric Acid Reactive Substances
0
Testosterone
3XMK78S47O
Luteinizing Hormone
9002-67-9
Follicle Stimulating Hormone
9002-68-0
Catalase
EC 1.11.1.6
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
370-380Références
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