Head-to-head comparison of a CZT-based all-purpose SPECT camera and a dedicated CZT cardiac device for myocardial perfusion and functional analysis.


Journal

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 31 05 2019
accepted: 21 07 2019
pubmed: 7 8 2019
medline: 17 2 2022
entrez: 7 8 2019
Statut: ppublish

Résumé

To compare the outputs of a novel all-purpose SPECT camera equipped with CZT detectors (Discovery NM/CT 670) with the state-of-the-art represented by a dedicated CZT (Alcyone, Discovery 530c) cardiac camera in patients submitted to myocardial perfusion imaging (MPI). We included 19 patients that underwent sequential low-dose The two cameras showed excellent correlation for segmental myocardial % uptake at stress (R = 0.90; P < 0.001) and at rest (R = 0.88; P < 0.001) with narrow Bland-Altman limits of agreement. The level of diagnostic agreement of Discovery 670 and Alcyone cameras regarding perfusion analysis was excellent (Cohen's κ 0.85). Similarly, the two cameras showed excellent correlation in the evaluation of LV ejection fraction (R = 0.95), peak filling rate (R = 0.97), and mass (R = 0.98). Our preliminary results suggest that MPI with an all-purpose Discovery 670 CZT-SPECT camera is feasible, comparing well with the current state-of-the-art technology.

Identifiants

pubmed: 31385223
doi: 10.1007/s12350-019-01835-4
pii: 10.1007/s12350-019-01835-4
doi:

Substances chimiques

CdZnTe 0
Cadmium 00BH33GNGH
Zinc J41CSQ7QDS
Tellurium NQA0O090ZJ

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1323-1330

Informations de copyright

© 2019. American Society of Nuclear Cardiology.

Références

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Auteurs

Alessia Gimelli (A)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy. gimelli@ftgm.it.

Riccardo Liga (R)

Università di Pisa, Pisa, Italy.

Michelangelo Bertasi (M)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.

Annette Kusch (A)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.

Paolo Marzullo (P)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.
CNR, Institute of Clinical Physiology, Pisa, Italy.

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