Vulnerability of the developing airway.
Airway hyperreactivity
Prematurity
Wheezing disorders
Journal
Respiratory physiology & neurobiology
ISSN: 1878-1519
Titre abrégé: Respir Physiol Neurobiol
Pays: Netherlands
ID NLM: 101140022
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
08
04
2019
revised:
02
07
2019
accepted:
30
07
2019
pubmed:
7
8
2019
medline:
2
6
2020
entrez:
7
8
2019
Statut:
ppublish
Résumé
Longer term respiratory morbidity is a frequent concern for former preterm infants. Increased airway reactivity and wheezing disorders are extremely common in this population, both in infants who meet diagnostic criteria for bronchopulmonary dysplasia [BPD], and in the absence of this diagnosis. It is, therefore, imperative to gain a better understanding of normal and abnormal postnatal development of the immature airway. Airway hyperreactivity may be secondary to abnormal bronchoalveolar attachments in the face of parenchymal lung injury, or secondary to an imbalance between constrictor and dilator neural pathways. Finally, the airway itself may undergo functional and/or structural changes, including increased airway smooth muscle mass, and changes in airway extracellular matrix which may, in turn, modulate downstream signaling pathways to hyperoxia or pressure exposed vulnerable airways.
Identifiants
pubmed: 31386914
pii: S1569-9048(18)30325-2
doi: 10.1016/j.resp.2019.103263
pmc: PMC9760171
mid: NIHMS1854882
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
103263Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL056470
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL138402
Pays : United States
Informations de copyright
Copyright © 2019. Published by Elsevier B.V.
Références
Pediatr Res. 2015 Aug;78(2):145-51
pubmed: 25950451
PLoS Med. 2014 Jan 28;11(1):e1001596
pubmed: 24492409
Am J Respir Crit Care Med. 2005 Nov 15;172(10):1253-8
pubmed: 16109980
N Engl J Med. 2010 May 27;362(21):1970-9
pubmed: 20472939
J Appl Physiol (1985). 1989 Apr;66(4):1760-5
pubmed: 2732168
Am J Respir Crit Care Med. 2001 Jun;163(7):1723-9
pubmed: 11401896
Pediatr Res. 2017 Apr;81(4):565-571
pubmed: 27842056
Pediatrics. 2010 Jul;126(1):115-28
pubmed: 20530073
Eur Respir J. 1997 Jan;10(1):27-34
pubmed: 9032487
Am J Obstet Gynecol. 1998 Jul;179(1):194-202
pubmed: 9704787
Am J Respir Cell Mol Biol. 2000 Mar;22(3):280-8
pubmed: 10696064
Am J Physiol Lung Cell Mol Physiol. 2006 Sep;291(3):L447-56
pubmed: 16648236
Pediatrics. 2003 Mar;111(3):469-76
pubmed: 12612223
Matrix Biol. 2019 May;78-79:255-271
pubmed: 30098420
Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L208-L216
pubmed: 27913427
Paediatr Respir Rev. 2017 Jan;21:27-33
pubmed: 27639458
Am J Public Health. 1997 Feb;87(2):205-9
pubmed: 9103098
J Allergy Clin Immunol. 2008 Apr;121(4):878-84.e6
pubmed: 18313129
J Perinatol. 2019 Jan;39(1):86-94
pubmed: 30353082
N Engl J Med. 1967 Feb 16;276(7):357-68
pubmed: 5334613
JAMA. 2018 Jun 5;319(21):2190-2201
pubmed: 29872859
Am J Physiol Lung Cell Mol Physiol. 2005 Aug;289(2):L307-14
pubmed: 15821016
Respir Physiol Neurobiol. 2003 Sep 16;137(2-3):361-72
pubmed: 14516738
Respir Physiol Neurobiol. 2012 May 31;181(3):308-20
pubmed: 22484819
Semin Fetal Neonatal Med. 2010 Aug;15(4):230-5
pubmed: 20452844
J Clin Invest. 1997 Jun 15;99(12):2992-9
pubmed: 9185523
Semin Perinatol. 2018 Nov;42(7):459-470
pubmed: 30446300
J Biol Chem. 2009 Apr 24;284(17):11309-17
pubmed: 19164299
Clin Perinatol. 2012 Sep;39(3):585-601
pubmed: 22954271
JAMA. 2011 Jul 27;306(4):394-401
pubmed: 21791688
Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15;303(8):L711-9
pubmed: 22923637
Ann Am Thorac Soc. 2016 Aug;13(8):1262-70
pubmed: 27222921
J Appl Physiol (1985). 2003 Apr;94(4):1403-9
pubmed: 12626471
J Appl Physiol (1985). 2004 May;96(5):1854-60
pubmed: 14766780
Am J Respir Crit Care Med. 2010 May 15;181(10):1093-7
pubmed: 20133928
Pediatr Res. 2019 Feb;85(3):318-323
pubmed: 30538265
Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L35-44
pubmed: 17384081
Am J Physiol Lung Cell Mol Physiol. 2014 Aug 15;307(4):L295-301
pubmed: 24951774
Pediatrics. 2011 Feb;127(2):363-9
pubmed: 21220405
Am J Physiol. 1991 Dec;261(6 Pt 1):L370-7
pubmed: 1767857
Pediatrics. 2002 Feb;109(2):330-8
pubmed: 11826218
N Engl J Med. 2006 Jul 27;355(4):343-53
pubmed: 16870913
Pediatr Res. 2019 Jun;85(7):987-993
pubmed: 30374050
J Pediatr. 1997 Apr;130(4):570-6
pubmed: 9108855
J Pediatr. 2013 Mar;162(3):464-9
pubmed: 23140884
Neonatology. 2012;101(4):345-52
pubmed: 22940624
Pediatr Res. 2017 Feb;81(2):376-383
pubmed: 27925619
Clin Sci (Lond). 2018 Jan 25;132(2):273-284
pubmed: 29263136
Am J Obstet Gynecol. 2009 Feb;200(2):195.e1-10
pubmed: 19110233
Am J Obstet Gynecol. 1997 Oct;177(4):825-30
pubmed: 9369827
N Engl J Med. 2017 Jul 27;377(4):329-337
pubmed: 28745986
Eur Respir J. 1999 Jul;14(1):74-9
pubmed: 10489831
Semin Fetal Neonatal Med. 2012 Feb;17(1):30-5
pubmed: 21855435
Neonatology. 2014;105(1):39-45
pubmed: 24281398
J Allergy Clin Immunol. 2011 Aug;128(2):403-411.e3
pubmed: 21570715
J Perinatol. 2019 Feb;39(2):203-211
pubmed: 30367103
J Paediatr Child Health. 1996 Aug;32(4):339-43
pubmed: 8844542
J Appl Physiol (1985). 2000 Sep;89(3):1205-12
pubmed: 10956370
Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L529-35
pubmed: 15908474
J Appl Physiol (1985). 1993 Mar;74(3):1437-43
pubmed: 8482688
Am J Respir Cell Mol Biol. 2015 Feb;52(2):162-70
pubmed: 25004109
Med Klin Intensivmed Notfmed. 2018 Feb;113(Suppl 1):2-6
pubmed: 29116360
J Appl Physiol (1985). 2000 Jul;89(1):228-34
pubmed: 10904056
Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L68-73
pubmed: 17215435
Am J Physiol. 1993 Jun;264(6 Pt 1):L606-14
pubmed: 8333552
Am J Respir Cell Mol Biol. 1995 Dec;13(6):629-38
pubmed: 7576700