Hormones in Breast Milk and Effect on Infants' Growth: A Systematic Review.
adipokines
body composition
breast milk
growth
hormones
term infant
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
09 Aug 2019
09 Aug 2019
Historique:
received:
19
07
2019
revised:
06
08
2019
accepted:
07
08
2019
entrez:
10
8
2019
pubmed:
10
8
2019
medline:
6
2
2020
Statut:
epublish
Résumé
Breast milk is characterized by a dynamic and complex composition which includes hormones and other bioactive components that could influence infant growth, development, and optimize health. Among the several beneficial effects associated with prolonged breastfeeding, a 13% decrease in the risk of overweight and obesity has been reported. Recent research has focused on breast milk hormones contributing to the appetite and energy balance regulation and adiposity. Accordingly, we conducted a literature systematic review with the aim to provide an update on the effect of leptin, ghrelin, Insulin Growth Factor 1, adiponectin, and insulin on infants' and children's growth and body composition. The revised literature reveals contrasting findings concerning the potential role of all these hormones on modeling growth and fat mass apposition and health outcomes later in life. Further studies are needed to gain further insight into the specific role of these bioactive components in metabolic pathways related to body composition. This could help gain a further insight on infants' growth, both in physiological and pathological settings.
Identifiants
pubmed: 31395844
pii: nu11081845
doi: 10.3390/nu11081845
pmc: PMC6724322
pii:
doi:
Substances chimiques
Hormones
0
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
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