Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing

Animals Drosophila Proteins / metabolism Drosophila melanogaster / embryology Frizzled Receptors / metabolism Membrane Glycoproteins / metabolism Wings, Animal / embryology Wnt Signaling Pathway / physiology Wnt1 Protein / metabolism
Drosophila Frizzled Fz2 Morphogen gradient formation Protein secretion Wg Wing epithelium Wnt

Journal

Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744

Informations de publication

Date de publication:
09 08 2019
Historique:
received: 09 12 2018
accepted: 10 07 2019
entrez: 11 8 2019
pubmed: 11 8 2019
medline: 24 6 2020
Statut: epublish

Résumé

Wnts are secreted proteins that regulate cell fate during development of all metazoans. Wnt proteins were proposed to spread over several cells to activate signaling directly at a distance. In the

Identifiants

DOI: 10.1242/dev.174789 PMID: 31399474 PMC: PMC6703709
pubmed: 31399474
pii: 146/15/dev174789
doi: 10.1242/dev.174789
pmc: PMC6703709
pii:
doi:

Substances chimiques

Drosophila Proteins 0
Frizzled Receptors 0
Membrane Glycoproteins 0
Nrt protein, Drosophila 0
Wnt1 Protein 0
fz2 protein, Drosophila 0
wg protein, Drosophila 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2019. Published by The Company of Biologists Ltd.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing or financial interests.

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Auteurs

Varun Chaudhary (V)

German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics and Department of Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany m.boutros@dkfz.de varun.c@iiserb.ac.in.
Department of Biological Science, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, Bhopal 462066, India.
ORCID: 0000-0001-9604-4806

Swapnil Hingole (S)

Department of Biological Science, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, Bhopal 462066, India.

Jana Frei (J)

German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics and Department of Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

Fillip Port (F)

German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics and Department of Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

David Strutt (D)

Department of Biomedical Science, University of Sheffield, Sheffield S10 2TN, UK.

Michael Boutros (M)

German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics and Department of Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany m.boutros@dkfz.de varun.c@iiserb.ac.in.
ORCID: 0000-0002-9458-817X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'arthropode › Protéines d'insecte › Protéines de Drosophila › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs Wnt › Récepteurs Frizzled › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Glycoprotéines membranaires › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Structures anatomiques de l'animal › Membre thoracique › Ailes d'animaux › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Voie de signalisation Wnt › Robust Wnt signaling is maintained by a Wg...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines de type Wingless › Protéine Wnt1 › Robust Wnt signaling is maintained by a Wg...