The C-terminal domain of the MERS coronavirus M protein contains a
MERS-CoV
Middle East respiratory syndrome
coronavirus
endoplasmic reticulum (ER)
intracellular trafficking
plasma membrane
protein motif
protein sorting
trans-Golgi network localization
viral protein
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
27 09 2019
27 09 2019
Historique:
received:
18
04
2019
revised:
06
08
2019
pubmed:
11
8
2019
medline:
19
5
2020
entrez:
11
8
2019
Statut:
ppublish
Résumé
Coronavirus M proteins represent the major protein component of the viral envelope. They play an essential role during viral assembly by interacting with all of the other structural proteins. Coronaviruses bud into the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), but the mechanisms by which M proteins are transported from their site of synthesis, the ER, to the budding site remain poorly understood. Here, we investigated the intracellular trafficking of the Middle East respiratory syndrome coronavirus (MERS-CoV) M protein. Subcellular localization analyses revealed that the MERS-CoV M protein is retained intracellularly in the
Identifiants
pubmed: 31399512
pii: S0021-9258(20)34998-X
doi: 10.1074/jbc.RA119.008964
pmc: PMC6768645
doi:
Substances chimiques
Protein Sorting Signals
0
Viral Matrix Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
14406-14421Informations de copyright
© 2019 Perrier et al.
Références
J Virol. 1999 Sep;73(9):7441-52
pubmed: 10438834
J Virol. 1999 Oct;73(10):7952-64
pubmed: 10482542
J Virol. 2000 Jun;74(11):4967-78
pubmed: 10799570
J Biol Chem. 2001 May 18;276(20):17515-23
pubmed: 11278557
EMBO J. 2001 Dec 3;20(23):6742-50
pubmed: 11726510
Mol Biol Cell. 2003 Jan;14(1):142-55
pubmed: 12529433
J Gen Virol. 2005 May;86(Pt 5):1423-34
pubmed: 15831954
Curr Opin Cell Biol. 2005 Aug;17(4):369-75
pubmed: 15975779
Adv Virus Res. 2005;64:165-230
pubmed: 16139595
J Biol Chem. 1992 Jul 15;267(20):14094-101
pubmed: 1629209
Adv Virus Res. 2006;66:193-292
pubmed: 16877062
J Cell Sci. 1991 Apr;98 ( Pt 4):567-75
pubmed: 1860903
J Virol. 2008 Nov;82(22):11318-30
pubmed: 18753196
Nat Rev Microbiol. 2009 Jun;7(6):439-50
pubmed: 19430490
Cell Mol Life Sci. 2010 Jan;67(1):29-41
pubmed: 19727557
J Virol. 2010 Feb;84(4):1891-901
pubmed: 20007283
J Biol Chem. 2010 Apr 23;285(17):12862-72
pubmed: 20154085
J Virol. 2010 Nov;84(21):11418-28
pubmed: 20719948
Am J Physiol Cell Physiol. 2011 Apr;300(4):C723-42
pubmed: 21209361
Proc Natl Acad Sci U S A. 1990 Sep;87(18):6944-8
pubmed: 2169615
Viruses. 2012 Mar;4(3):363-82
pubmed: 22590676
Viruses. 2012 Apr;4(4):557-80
pubmed: 22590686
Viruses. 2012 Jun;4(6):1011-33
pubmed: 22816037
Trends Cell Biol. 2014 Jan;24(1):9-18
pubmed: 24076263
Protein Cell. 2013 Dec;4(12):951-61
pubmed: 24318862
Curr Biol. 2014 Feb 3;24(3):R130-6
pubmed: 24502791
Biochem Soc Trans. 2014 Oct;42(5):1453-9
pubmed: 25233431
J Virol. 2015 Sep;89(18):9313-23
pubmed: 26136577
Viruses. 2015 Jul 03;7(7):3552-73
pubmed: 26151305
J Cell Biol. 1987 Sep;105(3):1205-14
pubmed: 2821010
Adv Virus Res. 2018;100:163-188
pubmed: 29551135
J Virol. 2019 May 15;93(11):
pubmed: 30867314
J Cell Biol. 1995 Oct;131(2):339-49
pubmed: 7593163
J Biol Chem. 1995 Apr 14;270(15):8815-21
pubmed: 7721788
J Biol Chem. 1994 Nov 11;269(45):28263-9
pubmed: 7961764
J Virol. 1994 Oct;68(10):6523-34
pubmed: 8083990
J Cell Biol. 1994 Apr;125(2):253-68
pubmed: 8163544
Mol Biol Cell. 1993 Jul;4(7):695-704
pubmed: 8400455
EMBO J. 1993 May;12(5):2219-28
pubmed: 8491209
EMBO J. 1996 Apr 15;15(8):2020-8
pubmed: 8617249
J Virol. 1998 Aug;72(8):6838-50
pubmed: 9658133
J Virol. 1998 Nov;72(11):8636-43
pubmed: 9765403