How does gestational age affect growth and body composition of preterm twins?
Age Factors
Birth Weight
Body Composition
Bottle Feeding
Breast Feeding
Child Development
Gestational Age
Humans
Infant
Infant Formula
Infant Nutritional Physiological Phenomena
Infant, Low Birth Weight
/ growth & development
Infant, Newborn
Infant, Premature
/ growth & development
Nutritional Status
Retrospective Studies
Twins, Dizygotic
Twins, Monozygotic
Weight Gain
Journal
Pediatric research
ISSN: 1530-0447
Titre abrégé: Pediatr Res
Pays: United States
ID NLM: 0100714
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
24
08
2018
accepted:
25
07
2019
revised:
03
06
2019
pubmed:
12
8
2019
medline:
26
1
2021
entrez:
12
8
2019
Statut:
ppublish
Résumé
Twins experience altered growth compared to singletons. The primary aim of this study was to compare growth and body composition (BC) of twin and singleton preterm infants from birth to 3 months according to gestational age (GA). Secondary aims were to evaluate the effect of chorionicity and mode of feeding on twins' BC. Anthropometric measurements and BC were performed at term and 3 months in preterm infants (GA < 37 weeks). Infants were categorized as: extremely, very, moderate and late preterm infants. Chorionicity was assigned as monochorionic, dichorionic or multichorionic. Mode of feeding was recorded as any human milk feeding vs formula feeding. Five hundred and seventy-six preterm infants were included (223 twins). Late-preterm twins were lighter and shorter at each study point; fat-free mass (FFM) was lower in these infants at each study point, compared to singletons. No differences were found between twins and singleton on the other category. Multichorionic infants had an FFM deficit compared to monochorionic and dichorionic at term, whereas no differences were found at 3 months. FFM at term was negatively associated with being twin and formula-fed. Twins and singletons born before 34 weeks' GA showed similar anthropometry and BC. Conversely, twin late-preterm infants showed different growth and BC compared to singletons.
Sections du résumé
BACKGROUND
Twins experience altered growth compared to singletons. The primary aim of this study was to compare growth and body composition (BC) of twin and singleton preterm infants from birth to 3 months according to gestational age (GA). Secondary aims were to evaluate the effect of chorionicity and mode of feeding on twins' BC.
METHODS
Anthropometric measurements and BC were performed at term and 3 months in preterm infants (GA < 37 weeks). Infants were categorized as: extremely, very, moderate and late preterm infants. Chorionicity was assigned as monochorionic, dichorionic or multichorionic. Mode of feeding was recorded as any human milk feeding vs formula feeding.
RESULTS
Five hundred and seventy-six preterm infants were included (223 twins). Late-preterm twins were lighter and shorter at each study point; fat-free mass (FFM) was lower in these infants at each study point, compared to singletons. No differences were found between twins and singleton on the other category. Multichorionic infants had an FFM deficit compared to monochorionic and dichorionic at term, whereas no differences were found at 3 months. FFM at term was negatively associated with being twin and formula-fed.
CONCLUSIONS
Twins and singletons born before 34 weeks' GA showed similar anthropometry and BC. Conversely, twin late-preterm infants showed different growth and BC compared to singletons.
Identifiants
pubmed: 31401647
doi: 10.1038/s41390-019-0530-5
pii: 10.1038/s41390-019-0530-5
doi:
Types de publication
Comparative Study
Journal Article
Twin Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
57-61Références
Burgess, J. L. et al. Risk of late-preterm stillbirth and neonatal morbidity for monochorionic and dichorionic twins. Am. J. Obstet. Gynecol. 210, 578 e1–9. (2014).
pubmed: 24607757
pmcid: 4176937
doi: 10.1016/j.ajog.2014.03.003
Hayes, E. J. et al. Very-low-birthweight neonates: do outcomes differ in multiple compared with singleton gestations? Am. J. Perinatol. 24, 373–376 (2007).
pubmed: 17566946
doi: 10.1055/s-2007-981852
Loos, R. J. F. et al. Determinants of birthweight and intrauterine growth in liveborn twins. Paediatr. Perinat. Epidemiol. 19, 15–22 (2005).
pubmed: 15670117
doi: 10.1111/j.1365-3016.2005.00611.x
Zhang, J. et al. An adjustable fetal weight standard for twins: a statistical modeling study. BMC Med. 13, 159 (2015).
pubmed: 26141190
pmcid: 4491250
doi: 10.1186/s12916-015-0401-9
Mendez-Figueroa, H. et al. Growth among twins: use of singleton versus twin-specific growth nomograms. Am. J. Perinatol. 35, 184–191 (2018).
pubmed: 28873489
doi: 10.1055/s-0037-1606381
Ghi, T. et al. Development of customized fetal growth charts in twins. Am. J. Obstet. Gynecol. 216, 514.e1–514.e17 (2017).
doi: 10.1016/j.ajog.2016.12.176
van Dommelen, P. et al. Growth references for height, weight and body mass index of twins aged 0–2.5 years. Acta Paediatr. 97, 1099–1104 (2008).
pubmed: 18460042
doi: 10.1111/j.1651-2227.2008.00853.x
Liu, Y. C. & Blair, E. M. Predicted birthweight for singletons and twins. Twin Res. 5, 529–537 (2002).
pubmed: 12573184
doi: 10.1375/136905202762341991
Hennequin, Y. et al. Twins: interpretation of height-weight curves at birth. Rev. Med. Brux. 20, 81–85 (1999).
pubmed: 10335101
Roggero, P. et al. Measuring the body composition of preterm and term neonates: from research to clinical applications. J. Pediatr. Gastroenterol. Nutr. 45, 159–162 (2007).
doi: 10.1097/01.mpg.0000302964.85922.1a
Wells, J. C., Chomtho, S. & Fewtrell, M. S. Programming of body composition by early growth and nutrition. Proc. Nutr. Soc. 66, 423–434 (2007).
pubmed: 17637095
doi: 10.1017/S0029665107005691
Roggero, P. et al. Is term newborn body composition being achieved postnatally in preterm infants? Early Hum. Dev. 85, 349–352 (2009).
pubmed: 19162413
doi: 10.1016/j.earlhumdev.2008.12.011
Paviotti, G. et al. Longitudinal growth and body composition of twins versus singletons in the first month of life. Sci. World J. 2013, 108189 (2013).
doi: 10.1155/2013/108189
Demarini, S., Koo, W. W. K. & Hockman, E. M. Bone, lean and fat mass of newborn twins versus singletons. Acta Paediatr. 95, 594–599 (2006).
pubmed: 16825141
doi: 10.1080/08035250500462091
Johnson, M. J. et al. Preterm birth and body composition at term equivalent age: a systematic review and meta-analysis. Paediatrics 130, e640–e649 (2012).
doi: 10.1542/peds.2011-3379
Giannì, M. L. et al. Body composition in late preterm infants according to percentile at birth. Pediatr. Res. 79, 710–715 (2016).
pubmed: 26717003
doi: 10.1038/pr.2015.273
Fenton, T. R. & Kim, J. H. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 13, 59 (2013).
pubmed: 23601190
pmcid: 3637477
doi: 10.1186/1471-2431-13-59
Blencowe, H. et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 379, 2162–2172 (2012).
pubmed: 22682464
doi: 10.1016/S0140-6736(12)60820-4
Engle, W. A. American Academy of Pediatrics Committee on Fetus and Newborn. Age terminology during the perinatal period. Pediatrics 114, 1362–1364 (2004).
pubmed: 15520122
doi: 10.1542/peds.2004-1915
Hehir, M. P. et al. Prenatal prediction of significant intertwin birthweight discordance using standard second and third trimester sonographic parameters. Acta Obstet. Gynecol. Scand. 96, 472–478 (2017).
pubmed: 28052317
doi: 10.1111/aogs.13092
Agostoni, C. et al. Growth patterns of breast fed and formula fed infants in the first 12 months of life: an Italian study. Arch. Dis. Child. 81, 395–399 (1999).
pubmed: 10519710
pmcid: 1718130
doi: 10.1136/adc.81.5.395
Ma, G. et al. Validation of a new pediatric air displacement plethysmograph for assessing body composition in infants. Am. J. Clin. Nutr. 79, 653–660 (2004).
pubmed: 15051611
doi: 10.1093/ajcn/79.4.653
Ellis, K. J. et al. Body composition assessment in infancy: air-displacement plethysmography compared with a reference 4-compartment model. Am. J. Clin. Nutr. 85, 90–95 (2007).
pubmed: 17209182
doi: 10.1093/ajcn/85.1.90
Fomon, S. J. et al. Body composition of reference children from birth to age 10 years. Am. J. Clin. Nutr. 35, 1169–1175 (1982).
pubmed: 7081099
doi: 10.1093/ajcn/35.5.1169
Section on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics 129, e827–e841 (2012).
doi: 10.1542/peds.2011-3552
Liu, P. et al. The utility of fat mass index vs. body mass index and percentage of body fat in the screening of metabolic syndrome. BMC Public Health 13, 629 (2013).
pubmed: 23819808
pmcid: 3703297
doi: 10.1186/1471-2458-13-629
Liotto, N. et al. Is fat mass accretion of late preterm infants associated with insulin resistance? Neonatology 111, 353–359 (2017).
pubmed: 28092917
doi: 10.1159/000453523
Huang, P. et al. Effects of breast-feeding compared with formula-feeding on preterm infant body composition: a systematic review and meta-analysis. Br. J. Nutr. 116, 132–141 (2016).
pubmed: 27181767
doi: 10.1017/S0007114516001720
Giannì, M. L. et al. Postnatal catch-up fat after late preterm birth. Pediatr. Res. 72, 637–640 (2012).
pubmed: 23011446
doi: 10.1038/pr.2012.128
Grantz, K. et al. Dichorionic twin trajectories: the NICHD Fetal Growth Studies. Am. J. Obstet. Gynecol. 215, 221 (2016).
pubmed: 27143399
pmcid: 4967402
doi: 10.1016/j.ajog.2016.04.044
Jelenkovic, A. et al. Zygosity differences in height and body mass index of twins from infancy to old age: a study of the CODATwins Project. Twin Res. Hum. Genet. 18, 557–570 (2015).
pubmed: 26337138
pmcid: 4605819
doi: 10.1017/thg.2015.57