Improved analysis of captan, tetrahydrophthalimide, captafol, folpet, phthalimide, and iprodione in fruits and vegetables by liquid chromatography tandem mass spectrometry.
Aminoimidazole Carboxamide
/ analogs & derivatives
Captan
/ analogs & derivatives
Chromatography, Liquid
/ methods
Cyclohexenes
/ analysis
Food Contamination
/ analysis
Fruit
/ chemistry
Hydantoins
/ analysis
Limit of Detection
Pesticide Residues
/ analysis
Phthalimides
/ analysis
Tandem Mass Spectrometry
/ methods
Vegetables
/ chemistry
Electrospray ionization
LC-MS/MS
Multiresidue analysis
Residue analysis of captan, captafol and folpet
Residue analysis of iprodione
Residue analysis of tetrahydrophthalimide and phthalimide
Journal
Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639
Informations de publication
Date de publication:
15 Dec 2019
15 Dec 2019
Historique:
received:
01
05
2018
revised:
10
07
2019
accepted:
20
07
2019
pubmed:
14
8
2019
medline:
7
11
2019
entrez:
13
8
2019
Statut:
ppublish
Résumé
An improved liquid chromatography tandem mass spectrometry method is reported for the determination of residues of captan (+tetrahydrophthalimide), captafol, folpet (+phthalimide), and iprodione in fruits and vegetables. The optimized electrospray ionization parameters (high cone gas flow, and a low desolvation temperature) did not result in degradation of target compounds, rather they provided a significant advantage over the conventional GC-MS/MS methods, which lack sensitivity and repeatability. Strategies for minimizing losses in recovery of these compounds during sample preparation included cryogenic comminution, extraction with acidified ethyl acetate or acetonitrile, and dilution of the final extract with acidified water prior to LC-MS/MS analysis. The method performance complied with the SANTE/11813/2017 guidelines, with recoveries in the range of 70-120% at the LOQ of 0.01 mg/kg across the tested matrices at various pHs. The efficiency of the method was reflected in its precision (RSDs < 10%) for incurred residues.
Identifiants
pubmed: 31404804
pii: S0308-8146(19)31324-X
doi: 10.1016/j.foodchem.2019.125216
pii:
doi:
Substances chimiques
Cyclohexenes
0
Hydantoins
0
Pesticide Residues
0
Phthalimides
0
phthalimide
1J6PQ7YI80
tetrahydrophthalimide
27813-21-4
Aminoimidazole Carboxamide
360-97-4
captafol
D88BWD4H64
Captan
EOL5G26Q9F
iprodione
S3AYV2A6EU
folpet
X5NFK36917
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
125216Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.