Greater Suppression of Glucagon, Lipolysis, and Ketogenesis with Insulin Glargine U300 as Compared with Glargine U100 in Type 1 Diabetes Mellitus.

Adult Diabetes Mellitus, Type 1 / blood Glucagon / blood Humans Hypoglycemic Agents / administration & dosage Insulin Glargine / administration & dosage Lipolysis / drug effects Middle Aged
Glargine U300 Glucagon Ketogenesis Lipolysis Type 1 diabetes

Journal

Diabetes technology & therapeutics
ISSN: 1557-8593
Titre abrégé: Diabetes Technol Ther
Pays: United States
ID NLM: 100889084

Informations de publication

Date de publication:
01 2020
Historique:
pubmed: 15 8 2019
medline: 6 11 2020
entrez: 15 8 2019
Statut: ppublish

Résumé

The aim of this study was to establish the effects of clinical doses of Gla-300 versus Gla-100 on suppression of glucagon, lipolysis, and ketogenesis in type 1 diabetes mellitus (T1DM). Eighteen persons with T1DM (age 40 ± 12 years, diabetes duration 26 ± 12 years, body mass index 23.4 ± 2 kg/m

Identifiants

DOI: 10.1089/dia.2019.0231 PMID: 31411498
pubmed: 31411498
doi: 10.1089/dia.2019.0231
doi:

Substances chimiques

Hypoglycemic Agents 0
Insulin Glargine 2ZM8CX04RZ
Glucagon 9007-92-5

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

57-61

Auteurs

Paola Lucidi (P)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

Francesca Porcellati (F)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

Patrizia Cioli (P)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

Paola Candeloro (P)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

Anna Marinelli Andreoli (A)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

Geremia B Bolli (GB)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

Carmine G Fanelli (CG)

Section of Endocrinology & Metabolism, Department of Medicine, Perugia University School of Medicine, Perugia, Italy.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Diabète de type 1 › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Glucagon › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hypoglycémiants › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline à longue durée d'action › Insuline glargine › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Métabolisme › Métabolisme lipidique › Lipolyse › Greater Suppression of Glucagon, Lipolysis,...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Greater Suppression of Glucagon, Lipolysis,...