The gastrointestinal fate of limonin and its effect on gut microbiota in mice.

Animals Bacteria / classification Colon / metabolism Female Gastrointestinal Microbiome Gastrointestinal Tract / metabolism Limonins / metabolism Male Mice

Journal

Food & function
ISSN: 2042-650X
Titre abrégé: Food Funct
Pays: England
ID NLM: 101549033

Informations de publication

Date de publication:
01 Sep 2019
Historique:
pubmed: 17 8 2019
medline: 8 2 2020
entrez: 17 8 2019
Statut: ppublish

Résumé

The gut microbiota plays a critical role in human health. Diets could modulate the gut microbiota, which in turn may contribute to altered health outcomes by way of changing the relative risk of chronic diseases. Limonin, widely found in citrus fruits, has been reported to possess multiple beneficial health effects. However, the gastrointestinal fate of limonin and its effect on gut microbiota remain unknown. Herein, mice were fed a diet containing 0.05% limonin (w/w) for 9 weeks. Liquid chromatography-mass spectrum analysis showed that limonin was concentrated along the gastrointestinal tract and reached 523.14 nmol g

Identifiants

DOI: 10.1039/c9fo01274e PMID: 31418448 PMC: PMC6751002
pubmed: 31418448
doi: 10.1039/c9fo01274e
pmc: PMC6751002
mid: NIHMS1047465
doi:

Substances chimiques

Limonins 0
limonin L0F260866S

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5521-5530

Subventions

Organisme : NCCIH NIH HHS
ID : R01 AT010229
Pays : United States

Références

Carcinogenesis. 2001 Jan;22(1):193-8
pubmed: 11159759
J Agric Food Chem. 2003 Jul 2;51(14):4156-61
pubmed: 12822961
Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15718-23
pubmed: 15505215
Appl Environ Microbiol. 2005 Dec;71(12):8228-35
pubmed: 16332807
Eur J Drug Metab Pharmacokinet. 2005 Oct-Dec;30(4):243-8
pubmed: 16435568
Biol Pharm Bull. 2006 Feb;29(2):191-201
pubmed: 16462017
Science. 2006 Jun 2;312(5778):1355-9
pubmed: 16741115
Appl Environ Microbiol. 2006 Jul;72(7):5069-72
pubmed: 16820507
Semin Immunol. 2007 Apr;19(2):94-105
pubmed: 17035042
Nature. 2006 Dec 21;444(7122):1022-3
pubmed: 17183309
J Chem Inf Model. 2007 Mar-Apr;47(2):460-3
pubmed: 17381169
J Agric Food Chem. 2007 Oct 17;55(21):8285-94
pubmed: 17892257
J Appl Microbiol. 2007 Oct;103(4):836-44
pubmed: 17897185
Bratisl Lek Listy. 2007;108(8):354-8
pubmed: 18203540
Cell Host Microbe. 2008 Apr 17;3(4):213-23
pubmed: 18407065
Appl Environ Microbiol. 2009 Mar;75(6):1534-45
pubmed: 19168652
Gastroenterology. 2009 Nov;137(5):1716-24.e1-2
pubmed: 19706296
Nat Methods. 2010 May;7(5):335-6
pubmed: 20383131
Microbiol Mol Biol Rev. 2010 Sep;74(3):453-76
pubmed: 20805407
ISME J. 2011 Feb;5(2):169-72
pubmed: 20827291
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18933-8
pubmed: 20937875
Adv Immunol. 2010;107:243-74
pubmed: 21034976
Neurogastroenterol Motil. 2011 Mar;23(3):187-92
pubmed: 21303428
J Agric Food Chem. 2011 Mar 23;59(6):2314-23
pubmed: 21338095
Nat Rev Microbiol. 2011 Apr;9(4):279-90
pubmed: 21407244
Cell Host Microbe. 2011 May 19;9(5):390-403
pubmed: 21575910
Diabetes Obes Metab. 2012 Feb;14(2):112-20
pubmed: 21812894
Front Microbiol. 2011 Aug 01;2:166
pubmed: 21904534
Nature. 2012 May 09;486(7402):222-7
pubmed: 22699611
Cell. 2012 Aug 3;150(3):470-80
pubmed: 22863002
ISME J. 2013 Apr;7(4):707-17
pubmed: 23190729
Obesity (Silver Spring). 2013 Dec;21(12):E607-15
pubmed: 23526699
Nat Rev Immunol. 2013 May;13(5):321-35
pubmed: 23618829
J Nat Sci Biol Med. 2013 Jan;4(1):126-33
pubmed: 23633848
Proc Natl Acad Sci U S A. 2013 May 28;110(22):9066-71
pubmed: 23671105
Nat Biotechnol. 2013 Sep;31(9):814-21
pubmed: 23975157
Biomed Res Int. 2014;2014:208064
pubmed: 24579075
J Am Coll Nutr. 2013;32(6):399-406
pubmed: 24606713
Bioinformatics. 2014 Nov 1;30(21):3123-4
pubmed: 25061070
Behav Brain Res. 2015 Jan 15;277:32-48
pubmed: 25078296
Am J Phys Anthropol. 2014 Dec;155(4):652-64
pubmed: 25252073
J Clin Invest. 2014 Oct;124(10):4204-11
pubmed: 25271725
Nutrients. 2014 Dec 24;7(1):17-44
pubmed: 25545101
J Nutr Biochem. 2015 Jun;26(6):651-60
pubmed: 25762527
Br J Nutr. 2015 May 28;113(10):1558-70
pubmed: 25864430
Environ Microbiol. 2015 Dec;17(12):4954-64
pubmed: 26235304
J Clin Biochem Nutr. 2015 Jul;57(1):39-43
pubmed: 26236099
Genome Res. 2015 Oct;25(10):1558-69
pubmed: 26260972
Cell. 2015 Dec 3;163(6):1360-74
pubmed: 26638070
Environ Microbiol. 2016 Feb;18(2):307-10
pubmed: 26781441
Int J Biol Macromol. 2016 Aug;89:489-98
pubmed: 27164502
PLoS Biol. 2016 Aug 19;14(8):e1002533
pubmed: 27541692
Appl Environ Microbiol. 2017 Aug 17;83(17):null
pubmed: 28667113
Amino Acids. 2017 Dec;49(12):2083-2090
pubmed: 28932911
J Nutr Biochem. 2018 Jun;56:55-64
pubmed: 29454999
Gut. 1987 Oct;28(10):1221-7
pubmed: 3678950

Auteurs

Min Gu (M)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu.

Jin Sun (J)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu and School of Food Science and Technology, Jiangnan University, Wuxi, China.
ORCID: 0000-0002-8423-9216

Ce Qi (C)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu and School of Food Science and Technology, Jiangnan University, Wuxi, China.
ORCID: 0000-0001-8460-6939

Xiaokun Cai (X)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu.

Timothy Goulette (T)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu.

Mingyue Song (M)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu and Guangdong Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou, China.

Xiaomeng You (X)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu.

David A Sela (DA)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu.

Hang Xiao (H)

Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA. hangxiao@foodsci.umass.edu.
ORCID: 0000-0001-6194-2796

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The gastrointestinal fate of limonin and its...
questionsmedicales.fr › Bactéries › The gastrointestinal fate of limonin and its...
questionsmedicales.fr › Système digestif › Tube digestif › Tube digestif inférieur › Gros intestin › Côlon › The gastrointestinal fate of limonin and its...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › The gastrointestinal fate of limonin and its...
questionsmedicales.fr › Système digestif › Tube digestif › The gastrointestinal fate of limonin and its...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Triterpènes › Limonines › The gastrointestinal fate of limonin and its...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The gastrointestinal fate of limonin and its...