Congenital diaphragmatic hernia-associated cardiac dysfunction.


Journal

Seminars in perinatology
ISSN: 1558-075X
Titre abrégé: Semin Perinatol
Pays: United States
ID NLM: 7801132

Informations de publication

Date de publication:
02 2020
Historique:
pubmed: 20 8 2019
medline: 5 3 2021
entrez: 18 8 2019
Statut: ppublish

Résumé

There is increasing evidence that cardiac dysfunction is a key contributor to CDH pathophysiology. Dysfunction in both right and left ventricles is common in the early neonatal period, contributes to clinical disease severity, and is associated with adverse outcomes including death and ECMO use. Early and routine assessment of ventricular function and pulmonary artery pressure may guide individualized clinical decision-making, including use of pulmonary vasodilators, cardiotropes, ECMO, and timing of surgical repair. Minimizing cardiac dysfunction, whether by prenatal, postnatal or perinatal treatment strategies, may lead to improved outcome in CDH.

Identifiants

pubmed: 31420110
pii: S0146-0005(19)30102-8
doi: 10.1053/j.semperi.2019.07.007
pii:
doi:

Substances chimiques

Cardiotonic Agents 0
Vasodilator Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

151168

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Neil Patel (N)

Department of Neonatology, Royal Hospital for Children, 1345 Govan Road, Glasgow G51 4TF, UK. Electronic address: neilpatel1@nhs.net.

Anna Claudia Massolo (AC)

Department of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Florian Kipfmueller (F)

Department of Neonatology and Pediatric Critical Care Medicine, University of Bonn, Bonn, Germany.

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Classifications MeSH