Prevalence and characterization of methicillin-resistant Staphylococcus pseudintermedius from symptomatic companion animals in Northern Italy: Clonal diversity and novel sequence types.
Animals
Bacterial Typing Techniques
Cat Diseases
/ epidemiology
Cats
Dog Diseases
/ epidemiology
Dogs
Genetic Variation
Genotype
Italy
/ epidemiology
Methicillin
/ pharmacology
Methicillin Resistance
Microbial Sensitivity Tests
Multilocus Sequence Typing
Pets
/ microbiology
Prevalence
Staphylococcal Infections
/ epidemiology
Staphylococcus
/ classification
Antimicrobial-resistance
Cat
Dog
Methicillin-resistant Staphylococcus pseudintermedius
Microarray
Multilocus sequence typing
Journal
Comparative immunology, microbiology and infectious diseases
ISSN: 1878-1667
Titre abrégé: Comp Immunol Microbiol Infect Dis
Pays: England
ID NLM: 7808924
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
14
05
2019
revised:
20
06
2019
accepted:
26
06
2019
pubmed:
23
8
2019
medline:
6
2
2020
entrez:
23
8
2019
Statut:
ppublish
Résumé
The aim of this study was to assess the prevalence, the genotypic diversity, the antimicrobial resistance traits of canine and feline clinical methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates in a diagnostic laboratory in Italy during 2015-2016. All isolates were characterized by multilocus sequence typing (MLST), staphylococcal cassette chromosome (SCC)-mec typing and staphylococcal protein A (spa)-typing. The resistance profiles were assessed by antimicrobial susceptibility testing and confirmed genotypically by the detection of mecA gene and by microarray analyses. The prevalence of MRSP isolates was high (31.6%). All the strains were multidrug resistant and the most frequent clone was ST71-SCCmec type II-III. These results confirm a high prevalence of MRSP amongst clinical samples from pets in Italy. These isolates show multidrug resistance features that are of concern both in veterinary and human medicine for clinical and epidemiological reasons.
Identifiants
pubmed: 31437680
pii: S0147-9571(19)30118-3
doi: 10.1016/j.cimid.2019.101331
pii:
doi:
Substances chimiques
Methicillin
Q91FH1328A
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101331Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.