Model Performance Metrics in Assessing the Value of Adding Intraoperative Data for Death Prediction: Applications to Noncardiac Surgery.


Journal

Studies in health technology and informatics
ISSN: 1879-8365
Titre abrégé: Stud Health Technol Inform
Pays: Netherlands
ID NLM: 9214582

Informations de publication

Date de publication:
21 Aug 2019
Historique:
entrez: 24 8 2019
pubmed: 24 8 2019
medline: 11 9 2019
Statut: ppublish

Résumé

We tested the value of adding data from the operating room to models predicting in-hospital death. We assessed model performance using two metrics, the area under the receiver operating characteristic curve (AUROC) and the area under the precision-recall curve (AUPRC), to illustrate the differences in information they convey in the setting of class imbalance. Data was collected on 74,147 patients who underwent major noncardiac surgery and 112 unique features were extracted from electronic health records. Sets of features were incrementally added to models using logistic regression, naïve Bayes, random forest, and gradient boosted machine methods. AUROC increased as more features were added, but changes were small for some modeling approaches. In contrast, AUPRC, which reflects positive predicted value, exhibited improvements across all models. Using AUPRC highlighted the added value of intraoperative data, not seen consistently with AUROC, and that with class imbalance AUPRC may serve as the more clinically relevant criterion.

Identifiants

pubmed: 31437918
pii: SHTI190216
doi: 10.3233/SHTI190216
doi:

Types de publication

Journal Article

Langues

eng

Pagination

223-227

Auteurs

Victor J Lei (VJ)

Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Edward H Kennedy (EH)

Department of Statistics & Data Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

ThaiBinh Luong (T)

Predictive Healthcare, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

Xinwei Chen (X)

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Daniel E Polsky (DE)

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Kevin G Volpp (KG)

Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Veterans Health Administration, Department of Veterans Affairs, Philadelphia, Pennsylvania, USA.

Mark D Neuman (MD)

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Anesthesiology, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

John H Holmes (JH)

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Lee A Fleisher (LA)

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Department of Anesthesiology, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

Amol S Navathe (AS)

Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Veterans Health Administration, Department of Veterans Affairs, Philadelphia, Pennsylvania, USA.

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