Therapeutic Effects of Fucoidan: A Review on Recent Studies.


Journal

Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729

Informations de publication

Date de publication:
21 Aug 2019
Historique:
received: 29 06 2019
revised: 16 08 2019
accepted: 19 08 2019
entrez: 24 8 2019
pubmed: 24 8 2019
medline: 7 3 2020
Statut: epublish

Résumé

Fucoidan is a polysaccharide largely made up of l-fucose and sulfate groups. Fucoidan is favorable worldwide, especially amongst the food and pharmaceutical industry as a consequence of its promising therapeutic effects. Its applaudable biological functions are ascribed to its unique biological structure. Classical bioactivities associated with fucoidan include anti-oxidant, anti-tumor, anti-coagulant, anti-thrombotic, immunoregulatory, anti-viral and anti-inflammatory effects. More recently, a variety of in vitro and in vivo studies have been carried out to further highlight its therapeutic potentials. This review focuses on the progress towards understanding fucoidan and its biological activities, which may be beneficial as a future therapy. Hence, we have summarized in vitro and in vivo studies that were done within the current decade. We expect this review and a variety of others can contribute as a theoretical basis for understanding and inspire further product development of fucoidan.

Identifiants

pubmed: 31438588
pii: md17090487
doi: 10.3390/md17090487
pmc: PMC6780838
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents 0
Anticoagulants 0
Antineoplastic Agents 0
Antioxidants 0
Antiviral Agents 0
Fibrinolytic Agents 0
Immunologic Factors 0
Plant Extracts 0
Polysaccharides 0
fucoidan 9072-19-9

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Natural Science Foundation of China
ID : LY18C020006
Organisme : Science and Technology Program of Wenzhou
ID : Y20180210
Organisme : National Natural Science Foundation of China
ID : 41876197, 31470430 and 81872952

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Auteurs

Sibusiso Luthuli (S)

College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.

Siya Wu (S)

College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.

Yang Cheng (Y)

College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.

Xiaoli Zheng (X)

College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.

Mingjiang Wu (M)

College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China. wmj@wzu.edu.cn.

Haibin Tong (H)

College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China. tonghb@wzu.edu.cn.

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Classifications MeSH