Therapeutic Effects of Fucoidan: A Review on Recent Studies.
Animals
Anti-Inflammatory Agents
/ pharmacology
Anticoagulants
/ pharmacology
Antineoplastic Agents
/ pharmacology
Antioxidants
/ pharmacology
Antiviral Agents
/ pharmacology
Distemper
/ drug therapy
Fibrinolytic Agents
/ pharmacology
HIV Infections
/ drug therapy
Hepatitis B
/ drug therapy
Humans
Immunologic Factors
/ pharmacology
Influenza, Human
/ drug therapy
Metabolic Syndrome
/ drug therapy
Neoplasms
/ drug therapy
Plant Extracts
/ pharmacology
Polysaccharides
/ pharmacology
Seaweed
/ chemistry
Vascular Diseases
/ drug therapy
anti-viral
bioactivity
fucoidan
therapeutic effects
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
21 Aug 2019
21 Aug 2019
Historique:
received:
29
06
2019
revised:
16
08
2019
accepted:
19
08
2019
entrez:
24
8
2019
pubmed:
24
8
2019
medline:
7
3
2020
Statut:
epublish
Résumé
Fucoidan is a polysaccharide largely made up of l-fucose and sulfate groups. Fucoidan is favorable worldwide, especially amongst the food and pharmaceutical industry as a consequence of its promising therapeutic effects. Its applaudable biological functions are ascribed to its unique biological structure. Classical bioactivities associated with fucoidan include anti-oxidant, anti-tumor, anti-coagulant, anti-thrombotic, immunoregulatory, anti-viral and anti-inflammatory effects. More recently, a variety of in vitro and in vivo studies have been carried out to further highlight its therapeutic potentials. This review focuses on the progress towards understanding fucoidan and its biological activities, which may be beneficial as a future therapy. Hence, we have summarized in vitro and in vivo studies that were done within the current decade. We expect this review and a variety of others can contribute as a theoretical basis for understanding and inspire further product development of fucoidan.
Identifiants
pubmed: 31438588
pii: md17090487
doi: 10.3390/md17090487
pmc: PMC6780838
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Anticoagulants
0
Antineoplastic Agents
0
Antioxidants
0
Antiviral Agents
0
Fibrinolytic Agents
0
Immunologic Factors
0
Plant Extracts
0
Polysaccharides
0
fucoidan
9072-19-9
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Natural Science Foundation of China
ID : LY18C020006
Organisme : Science and Technology Program of Wenzhou
ID : Y20180210
Organisme : National Natural Science Foundation of China
ID : 41876197, 31470430 and 81872952
Références
Nat Prod Rep. 2007 Feb;24(1):31-86
pubmed: 17268607
Int J Biol Macromol. 2019 Jun 15;131:1162-1170
pubmed: 30974142
Circulation. 2006 Aug 22;114(8):e355-6
pubmed: 16923760
Arch Intern Med. 2007 Sep 10;167(16):1752-9
pubmed: 17846394
Food Res Int. 2017 Sep;99(Pt 3):1011-1020
pubmed: 28865611
Carbohydr Polym. 2015 Jan 22;115:122-8
pubmed: 25439876
Mar Drugs. 2018 Apr 18;16(4):null
pubmed: 29669995
J Nat Prod. 2011 Sep 23;74(9):1851-61
pubmed: 21875034
Int J Biol Macromol. 2016 Jan;82:249-55
pubmed: 26601762
Carbohydr Polym. 2018 Jul 15;192:208-216
pubmed: 29691015
Thromb Haemost. 2014 Mar 3;111(3):429-37
pubmed: 24285223
Virol J. 2017 Sep 16;14(1):178
pubmed: 28915824
Methods Find Exp Clin Pharmacol. 2005 Dec;27(10):705-10
pubmed: 16395421
Mar Drugs. 2019 Jul 29;17(8):null
pubmed: 31362412
Mar Drugs. 2019 Jun 01;17(6):null
pubmed: 31159355
PLoS One. 2015 Feb 18;10(2):e0118366
pubmed: 25692870
Vet Immunol Immunopathol. 2009 Jan 15;127(1-2):1-18
pubmed: 19019458
J Nutr Biochem. 2016 Jun;32:46-54
pubmed: 27142736
Mol Pharmacol. 2013 Jul;84(1):147-57
pubmed: 23658008
Carbohydr Res. 2003 Jan 20;338(2):153-65
pubmed: 12526839
Int J Mol Med. 2005 Apr;15(4):695-9
pubmed: 15754034
Carbohydr Res. 2004 Feb 25;339(3):511-7
pubmed: 15013388
Emerg Infect Dis. 2013 Feb;19(2):254-9
pubmed: 23343512
Carbohydr Res. 1991 Apr 2;211(1):77-90
pubmed: 1773433
Gut Microbes. 2012 Jan-Feb;3(1):29-34
pubmed: 22555633
Int J Biol Macromol. 2019 Jan;121:1145-1153
pubmed: 30340002
Mar Drugs. 2014 Dec 25;13(1):48-64
pubmed: 25546518
Biosci Biotechnol Biochem. 2010;74(2):350-7
pubmed: 20139614
Mar Drugs. 2018 Jul 30;16(8):null
pubmed: 30061499
Stroke. 1991 Jul;22(7):872-6
pubmed: 1906646
Virusdisease. 2014 Dec;25(4):474-80
pubmed: 25674625
Mar Drugs. 2018 Nov 12;16(11):null
pubmed: 30424528
Exp Eye Res. 2013 Oct;115:96-105
pubmed: 23810809
Mar Drugs. 2019 Jan 11;17(1):null
pubmed: 30641954
Int J Biol Macromol. 2008 Apr 1;42(3):235-40
pubmed: 18054382
Immunotargets Ther. 2018 Jun 07;7:35-49
pubmed: 29922629
Carbohydr Polym. 2013 Jan 2;91(1):1-6
pubmed: 23044098
Int J Biol Macromol. 2018 Dec;120(Pt B):1817-1822
pubmed: 30223052
Afr J Tradit Complement Altern Med. 2017 Jun 05;14(4):149-155
pubmed: 28638878
Acta Oncol. 2009;48(6):811-21
pubmed: 19513886
Nutrition. 2019 Sep;65:50-59
pubmed: 31029922
Lab Invest. 2014 Apr;94(4):382-93
pubmed: 24614196
Int J Biol Macromol. 2019 Mar 1;124:220-228
pubmed: 30496854
Biosecur Bioterror. 2010 Sep;8(3):243-54
pubmed: 20825335
Carbohydr Polym. 2019 May 15;212:178-185
pubmed: 30832845
J Ethnopharmacol. 2012 Aug 1;142(3):591-619
pubmed: 22683660
Sci Rep. 2017 Jan 17;7:40760
pubmed: 28094330
Hepatology. 2009 May;49(5 Suppl):S13-21
pubmed: 19399811
Carbohydr Res. 1999 Jun 30;319(1-4):154-65
pubmed: 10520264
Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2363-71
pubmed: 25304324
Carbohydr Res. 2001 Nov 8;336(2):155-9
pubmed: 11689185
Carbohydr Polym. 2019 Oct 1;221:157-165
pubmed: 31227154
Thromb Res. 2008;123 Suppl 1:S29-35
pubmed: 18835010
Int J Biol Macromol. 2016 Jan;82:83-8
pubmed: 26472515
Carbohydr Polym. 2013 Jun 5;95(1):606-14
pubmed: 23618312
Carbohydr Res. 2002 Apr 17;337(8):719-30
pubmed: 11950468
Biosci Biotechnol Biochem. 2013;77(2):235-42
pubmed: 23391903
Org Biomol Chem. 2015 Nov 14;13(42):10556-68
pubmed: 26340595
Mar Drugs. 2013 Aug 19;11(8):3000-14
pubmed: 23966033
Mar Biotechnol (NY). 2006 Jan-Feb;8(1):27-39
pubmed: 16222488
Food Funct. 2018 Oct 17;9(10):5371-5380
pubmed: 30264830
Carbohydr Res. 2006 Feb 6;341(2):238-45
pubmed: 16330004
Biomed Khim. 2017 Nov;63(6):553-558
pubmed: 29251618
Int J Biol Macromol. 2010 Jan 1;46(1):6-12
pubmed: 19883681
Nutr Cancer. 2009;61(3):340-7
pubmed: 19373607
N Engl J Med. 2009 Mar 5;360(10):953-6
pubmed: 19258250
Mar Drugs. 2018 Sep 09;16(9):null
pubmed: 30205616