Association between educational level and total and cause-specific mortality: a pooled analysis of over 694 000 individuals in the Asia Cohort Consortium.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
22 08 2019
Historique:
entrez: 25 8 2019
pubmed: 25 8 2019
medline: 28 8 2020
Statut: epublish

Résumé

To study the association of educational level and risk of death from all causes, cardiovascular disease (CVD) and cancer among Asian populations. A pooled analysis of 15 population-based cohort studies. 694 434 Asian individuals from 15 prospective cohorts within the Asia Cohort Consortium. None. HRs and 95% CIs for all-cause mortality, as well as for CVD-specific mortality and cancer-specific mortality. A total of 694 434 participants (mean age at baseline=53.2 years) were included in the analysis. During a mean follow-up period of 12.5 years, 103 023 deaths were observed, among which 33 939 were due to cancer and 34 645 were due to CVD. Higher educational levels were significantly associated with lower risk of death from all causes compared with a low educational level (≤primary education); HRs and 95% CIs for secondary education, trade/technical education and ≥university education were 0.88 (0.85 to 0.92), 0.81 (0.73 to 0.90) and 0.71 (0.63 to 0.80), respectively (p Higher educational level was associated with substantially lower risk of death among Asian populations.

Identifiants

pubmed: 31444178
pii: bmjopen-2018-026225
doi: 10.1136/bmjopen-2018-026225
pmc: PMC6707688
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e026225

Subventions

Organisme : NCI NIH HHS
ID : R01 CA082729
Pays : United States
Organisme : NIEHS NIH HHS
ID : R24 ES028532
Pays : United States
Organisme : NCI NIH HHS
ID : R37 CA070867
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA144034
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA173640
Pays : United States
Organisme : NIEHS NIH HHS
ID : P42 ES010349
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA107431
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK092949
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA182876
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA182910
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA102484
Pays : United States

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Keming Yang (K)

Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, Indiana, USA.

Ying Zhang (Y)

Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, USA.

Eiko Saito (E)

Division of Cancer Statistics Integration, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.

Md Shafiur Rahman (MS)

Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Prakash Chandra Gupta (PC)

Healis - Sekhsaria Institute for Public Health, Navi Mumbai, India.

Norie Sawada (N)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Akiko Tamakoshi (A)

Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.

Yu-Tang Gao (YT)

State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Woon-Puay Koh (WP)

Health Services and Systems Research, Duke-NUS Medical School, Singapore.

Xiao-Ou Shu (XO)

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Ichiro Tsuji (I)

Tohoku University Graduate School of Medicine, Sendai, Japan.

Atsuko Sadakane (A)

Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan.

Chisato Nagata (C)

Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.

San-Lin You (SL)

School of Medicine, Big Data Research Centre, Fu-Jen Catholic University, Taipei, Taiwan.

Jian-Min Yuan (JM)

Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Myung-Hee Shin (MH)

Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Seoul, The Republic of Korea.

Yu Chen (Y)

Department of Population Health, Department of Environmental Medicine, New York University School of Medicine, New York City, New York, USA.

Wen-Harn Pan (WH)

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

Mangesh S Pednekar (MS)

Healis - Sekhsaria Institute for Public Health, Navi Mumbai, India.

Shoichiro Tsugane (S)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Hui Cai (H)

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Yong-Bing Xiang (YB)

State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Kotaro Ozasa (K)

Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan.

Yasutake Tomata (Y)

Tohoku University Graduate School of Medicine, Sendai, Japan.

Seiki Kanemura (S)

Tohoku University Graduate School of Medicine, Sendai, Japan.

Yumi Sugawara (Y)

Tohoku University Graduate School of Medicine, Sendai, Japan.

Keiko Wada (K)

Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.

Renwei Wang (R)

Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Yoon-Ok Ahn (YO)

Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, The Republic of Korea.

Keun-Young Yoo (KY)

Armed Forces Capital Hospital, Seoul National University College of Medicine, Seoul, The Republic of Korea.

Habibul Ahsan (H)

Department of Public Health Sciences, The University of Chicago, Chicago, Illinois, USA.

Kee Seng Chia (KS)

Epidemiology Program, Saw Swee Hock School of Public Health, National University of Singapore, Singapore.

Paolo Boffetta (P)

Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Daehee Kang (D)

Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, The Republic of Korea.

John D Potter (JD)

Centre for Public Health Research, Massey University, Wellington, New Zealand.

Manami Inoue (M)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Wei Zheng (W)

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Hongmei Nan (H)

Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, Indiana, USA hnan@iu.edu.

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