[Stereotactic body radiotherapy. How to better protect normal tissues?]

Radiothérapie stéréotaxique extra crânienne. Comment mieux protéger les tissus sains ?

Journal

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
ISSN: 1769-6658
Titre abrégé: Cancer Radiother
Pays: France
ID NLM: 9711272

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 18 06 2019
revised: 10 07 2019
accepted: 11 07 2019
pubmed: 27 8 2019
medline: 8 10 2019
entrez: 27 8 2019
Statut: ppublish

Résumé

The use of stereotactic body radiotherapy (SBRT) has increased rapidly over the past decade. Optimal preservation of normal tissues is a major issue because of their high sensitivity to high doses per session. Extreme hypofractionation can convert random errors into systematic errors. Optimal preservation of organs at risk requires first of all a rigorous implementation of this technique according to published guidelines. The robustness of the imaging modalities used for planning, and training medical and paramedical staff are an integral part of these guidelines too. The choice of SBRT indications, dose fractionation, dose heterogeneity, ballistics, are also means of optimizing the protection of normal tissues. Non-coplanarity and tracking of moving targets allow dosimetric improvement in some clinical settings. Automatic planning could also improve normal tissue protection. Adaptive SBRT, with new image guided radiotherapy modalities such as MRI, could further reduce the risk of toxicity.

Identifiants

pubmed: 31447339
pii: S1278-3218(19)30329-4
doi: 10.1016/j.canrad.2019.07.153
pii:
doi:

Types de publication

Journal Article Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

630-635

Informations de copyright

Copyright © 2019 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

Auteurs

D Pasquier (D)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France; Centre de recherche en informatique, signal et automatique de Lille UMR CNRS 9189, université de Lille, M3, avenue Carl-Gauss, 59650 Villeneuve-d'Ascq, France. Electronic address: d-pasquier@o-lambret.fr.

T Lacornerie (T)

Service de physique médicale, centre Oscar-Lambret, 3, rue Combemale, 59020 Lille cedex, France.

X Mirabel (X)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France.

C Brassart (C)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France.

L Vanquin (L)

Service de physique médicale, centre Oscar-Lambret, 3, rue Combemale, 59020 Lille cedex, France.

E Lartigau (E)

Département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Combemale, 59020 Lille cedex, France; Centre de recherche en informatique, signal et automatique de Lille UMR CNRS 9189, université de Lille, M3, avenue Carl-Gauss, 59650 Villeneuve-d'Ascq, France.

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Classifications MeSH