The long-term outcome of an isolated vascular ring - A single-center experience.


Journal

Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590

Informations de publication

Date de publication:
12 2019
Historique:
received: 28 04 2019
accepted: 13 08 2019
pubmed: 29 8 2019
medline: 24 4 2020
entrez: 29 8 2019
Statut: ppublish

Résumé

The aim of this study is to document the long-term outcome of patients with a vascular ring. A single-center retrospective review of clinical symptoms was conducted in all patients born between 1980 and 2013, diagnosed with a complete vascular ring and at least 2 years of follow-up. Data were extracted from patient files and clinical symptoms were assessed by questionnaires sent to the parents. Age and diagnostic tools, type of surgery, postoperative complications, and the prevalence of clinical symptoms (stridor at rest, stridor with exercise, cough, exercise intolerance, dysphagia, and frequent respiratory infections) were reviewed. Fifty-one patients were included. The diagnosis was made before the age of 2 in 35/51. Surgery was performed in 41/51 patients with a limited number of reversible complications. The median follow-up was 8 (IQR 5-12) years. After 2 years, 21/51 patients were asymptomatic: 2/7 asymptomatic patients at diagnosis became symptomatic and symptoms resolved in 16/44 initially symptomatic patients. Consequently, 30/51 patients still had symptoms after 2 years. Of these, 16 had partial improvement, 5 stable symptoms, and 9 aggravation of symptoms. After 10 years, 26/36 patients were free of complaints. The most frequent long-term symptom was stridor. Surgical treatment of a congenital vascular ring is safe and mostly performed in patients with a double aortic arch. Conservative treatment for patients with little symptoms seems to be justifiable. A considerable number of patients have residual long-term symptoms after surgical relief of the vascular ring.

Sections du résumé

BACKGROUND AND OBJECTIVES
The aim of this study is to document the long-term outcome of patients with a vascular ring.
METHODS
A single-center retrospective review of clinical symptoms was conducted in all patients born between 1980 and 2013, diagnosed with a complete vascular ring and at least 2 years of follow-up. Data were extracted from patient files and clinical symptoms were assessed by questionnaires sent to the parents. Age and diagnostic tools, type of surgery, postoperative complications, and the prevalence of clinical symptoms (stridor at rest, stridor with exercise, cough, exercise intolerance, dysphagia, and frequent respiratory infections) were reviewed.
RESULTS
Fifty-one patients were included. The diagnosis was made before the age of 2 in 35/51. Surgery was performed in 41/51 patients with a limited number of reversible complications. The median follow-up was 8 (IQR 5-12) years. After 2 years, 21/51 patients were asymptomatic: 2/7 asymptomatic patients at diagnosis became symptomatic and symptoms resolved in 16/44 initially symptomatic patients. Consequently, 30/51 patients still had symptoms after 2 years. Of these, 16 had partial improvement, 5 stable symptoms, and 9 aggravation of symptoms. After 10 years, 26/36 patients were free of complaints. The most frequent long-term symptom was stridor.
CONCLUSION
Surgical treatment of a congenital vascular ring is safe and mostly performed in patients with a double aortic arch. Conservative treatment for patients with little symptoms seems to be justifiable. A considerable number of patients have residual long-term symptoms after surgical relief of the vascular ring.

Identifiants

pubmed: 31456344
doi: 10.1002/ppul.24490
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2028-2034

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Anouk Depypere (A)

Department of Pediatrics, Pediatric Pulmonology, University Hospital Leuven, Leuven, Belgium.

Marijke Proesmans (M)

Department of Pediatrics, Pediatric Pulmonology, University Hospital Leuven, Leuven, Belgium.

Björn Cools (B)

Department of Pediatrics, Congenital Cardiology, University Hospital Leuven, Leuven, Belgium.

François Vermeulen (F)

Department of Pediatrics, Pediatric Pulmonology, University Hospital Leuven, Leuven, Belgium.

Willem Daenen (W)

Department of Cardiac Surgery, University Hospital Leuven, Leuven, Belgium.

Bart Meyns (B)

Department of Cardiac Surgery, University Hospital Leuven, Leuven, Belgium.

Filip Rega (F)

Department of Cardiac Surgery, University Hospital Leuven, Leuven, Belgium.

Mieke Boon (M)

Department of Pediatrics, Pediatric Pulmonology, University Hospital Leuven, Leuven, Belgium.

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