Current status of the management and outcomes of acute aortic dissection in Japan: Analyses of nationwide Japanese Registry of All Cardiac and Vascular Diseases-Diagnostic Procedure Combination data.
Acute Disease
Aged
Aortic Dissection
/ diagnosis
Aortic Aneurysm, Thoracic
/ diagnosis
Diagnostic Techniques, Cardiovascular
/ statistics & numerical data
Disease Management
Female
Follow-Up Studies
Hospital Mortality
/ trends
Humans
Incidence
Japan
/ epidemiology
Male
Middle Aged
Prognosis
Registries
Retrospective Studies
Risk Factors
Treatment Outcome
Vascular Surgical Procedures
/ statistics & numerical data
Acute aortic dissection
Japanese Registry of All Cardiac and Vascular Diseases
medical cost
prognosis
Journal
European heart journal. Acute cardiovascular care
ISSN: 2048-8734
Titre abrégé: Eur Heart J Acute Cardiovasc Care
Pays: England
ID NLM: 101591369
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
pubmed:
29
8
2019
medline:
24
6
2021
entrez:
29
8
2019
Statut:
ppublish
Résumé
Despite recent advances in the diagnosis and management, the mortality of acute aortic dissection remains high. This study aims to clarify the current status of the management and outcome of acute aortic dissection in Japan. A total of 18,348 patients with acute aortic dissection (type A: 10,131, type B: 8217) in the Japanese Registry of All Cardiac and Vascular Diseases database between April 2012-March 2015 were studied. Characteristics, clinical presentation, management, and in-hospital outcomes were analyzed. Seasonal onset variation (autumn- and winter-dominant) was found in both types. More than 90% of patients underwent computed tomography for primary diagnosis. The overall in-hospital mortality of types A and B was 24.3% and 4.5%, respectively. The mortality in type A patients managed surgically was significantly lower than in those not receiving surgery (11.8% (799/6788) vs 49.7% (1663/3343); This nationwide study elucidated the clinical features and outcomes in contemporary patients with acute aortic dissections in real-world clinical practice in Japan.
Sections du résumé
BACKGROUND
BACKGROUND
Despite recent advances in the diagnosis and management, the mortality of acute aortic dissection remains high. This study aims to clarify the current status of the management and outcome of acute aortic dissection in Japan.
METHODS
METHODS
A total of 18,348 patients with acute aortic dissection (type A: 10,131, type B: 8217) in the Japanese Registry of All Cardiac and Vascular Diseases database between April 2012-March 2015 were studied. Characteristics, clinical presentation, management, and in-hospital outcomes were analyzed.
RESULTS
RESULTS
Seasonal onset variation (autumn- and winter-dominant) was found in both types. More than 90% of patients underwent computed tomography for primary diagnosis. The overall in-hospital mortality of types A and B was 24.3% and 4.5%, respectively. The mortality in type A patients managed surgically was significantly lower than in those not receiving surgery (11.8% (799/6788) vs 49.7% (1663/3343);
CONCLUSIONS
CONCLUSIONS
This nationwide study elucidated the clinical features and outcomes in contemporary patients with acute aortic dissections in real-world clinical practice in Japan.
Identifiants
pubmed: 31460772
doi: 10.1177/2048872619872847
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM