The flight response impairs cytoprotective mechanisms by activating the insulin pathway.
Active Transport, Cell Nucleus
Animals
Caenorhabditis elegans
/ cytology
Caenorhabditis elegans Proteins
/ metabolism
Cell Nucleus
/ metabolism
Cytoprotection
Forkhead Transcription Factors
/ metabolism
Insulin
/ metabolism
Insulin-Like Growth Factor I
/ metabolism
Intestinal Mucosa
/ metabolism
Longevity
Neurons
/ metabolism
Receptors, Adrenergic
/ metabolism
Receptors, Catecholamine
/ metabolism
Signal Transduction
Stress, Psychological
Tyramine
/ metabolism
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
received:
30
08
2018
accepted:
31
07
2019
pubmed:
30
8
2019
medline:
31
3
2020
entrez:
30
8
2019
Statut:
ppublish
Résumé
An animal's stress response requires different adaptive strategies depending on the nature and duration of the stressor. Whereas acute stressors, such as predation, induce a rapid and energy-demanding fight-or-flight response, long-term environmental stressors induce the gradual and long-lasting activation of highly conserved cytoprotective processes
Identifiants
pubmed: 31462774
doi: 10.1038/s41586-019-1524-5
pii: 10.1038/s41586-019-1524-5
pmc: PMC7986477
mid: NIHMS1536294
doi:
Substances chimiques
Caenorhabditis elegans Proteins
0
Forkhead Transcription Factors
0
Insulin
0
Receptors, Adrenergic
0
Receptors, Catecholamine
0
daf-16 protein, C elegans
0
tyramine receptor 3, C elegans
0
Insulin-Like Growth Factor I
67763-96-6
Tyramine
X8ZC7V0OX3
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
135-138Subventions
Organisme : NIH HHS
ID : P40 OD010440
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM084491
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS107475
Pays : United States
Références
Cannon, W. B. Bodily Changes in Pain, Hunger, Fear and Rage, an Account of Recent Researches into the Function of Emotional Excitement (D. Appleton and Co., 1915).
Prahlad, V., Cornelius, T. & Morimoto, R. I. Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons. Science 320, 811–814 (2008).
doi: 10.1126/science.1156093
Essers, M. A. et al. FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J. 23, 4802–4812 (2004).
doi: 10.1038/sj.emboj.7600476
Travers, M., Clinchy, M., Zanette, L., Boonstra, R. & Williams, T. D. Indirect predator effects on clutch size and the cost of egg production. Ecol. Lett. 13, 980–988 (2010).
pubmed: 20528899
Miller, M. W. & Sadeh, N. Traumatic stress, oxidative stress and post-traumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis. Mol. Psychiatry 19, 1156–1162 (2014).
doi: 10.1038/mp.2014.111
Rodriguez, M., Snoek, L. B., De Bono, M. & Kammenga, J. E. Worms under stress: C. elegans stress response and its relevance to complex human disease and aging. Trends Genet. 29, 367–374 (2013).
doi: 10.1016/j.tig.2013.01.010
Chalfie, M. et al. The neural circuit for touch sensitivity in Caenorhabditis elegans. J. Neurosci. 5, 956–964 (1985).
doi: 10.1523/JNEUROSCI.05-04-00956.1985
Wicks, S. R. & Rankin, C. H. Integration of mechanosensory stimuli in Caenorhabditis elegans. J. Neurosci. 15, 2434–2444 (1995).
doi: 10.1523/JNEUROSCI.15-03-02434.1995
Calabrese, E. J. Stress biology and hormesis: the Yerkes–Dodson law in psychology—a special case of the hormesis dose response. Crit. Rev. Toxicol. 38, 453–462 (2008).
doi: 10.1080/10408440802004007
Cypser, J. R. & Johnson, T. E. Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity. J. Gerontol. A Biol. Sci. Med. Sci. 57, B109–B114 (2002).
doi: 10.1093/gerona/57.3.B109
Kumsta, C., Chang, J. T., Schmalz, J. & Hansen, M. Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans. Nat. Commun. 8, 14337 (2017).
doi: 10.1038/ncomms14337
Rattan, S. I. & Ali, R. E. Hormetic prevention of molecular damage during cellular aging of human skin fibroblasts and keratinocytes. Ann. NY Acad. Sci. 1100, 424–430 (2007).
doi: 10.1196/annals.1395.047
Alkema, M. J., Hunter-Ensor, M., Ringstad, N. & Horvitz, H. R. Tyramine functions independently of octopamine in the Caenorhabditis elegans nervous system. Neuron 46, 247–260 (2005).
doi: 10.1016/j.neuron.2005.02.024
Pirri, J. K., McPherson, A. D., Donnelly, J. L., Francis, M. M. & Alkema, M. J. A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron 62, 526–538 (2009).
doi: 10.1016/j.neuron.2009.04.013
Maguire, S. M., Clark, C. M., Nunnari, J., Pirri, J. K. & Alkema, M. J. The C. elegans touch response facilitates escape from predacious fungi. Curr. Biol. 21, 1326–1330 (2011).
doi: 10.1016/j.cub.2011.06.063
Kagawa-Nagamura, Y., Gengyo-Ando, K., Ohkura, M. & Nakai, J. Role of tyramine in calcium dynamics of GABAergic neurons and escape behavior in Caenorhabditis elegans. Zoological Lett. 4, 19 (2018).
doi: 10.1186/s40851-018-0103-1
Zheng, M., Cao, P., Yang, J., Xu, X. Z. & Feng, Z. Calcium imaging of multiple neurons in freely behaving C. elegans. J. Neurosci. Methods 206, 78–82 (2012).
doi: 10.1016/j.jneumeth.2012.01.002
Komuniecki, R. W., Hobson, R. J., Rex, E. B., Hapiak, V. M. & Komuniecki, P. R. Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans? Mol. Biochem. Parasitol. 137, 1–11 (2004).
doi: 10.1016/j.molbiopara.2004.05.010
Tsalik, E. L. et al. LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. Dev. Biol. 263, 81–102 (2003).
doi: 10.1016/S0012-1606(03)00447-0
Wragg, R. T. et al. Tyramine and octopamine independently inhibit serotonin-stimulated aversive behaviors in Caenorhabditis elegans through two novel amine receptors. J. Neurosci. 27, 13402–13412 (2007).
doi: 10.1523/JNEUROSCI.3495-07.2007
Henderson, S. T. & Johnson, T. E. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr. Biol. 11, 1975–1980 (2001).
doi: 10.1016/S0960-9822(01)00594-2
Fontana, L., Partridge, L. & Longo, V. D. Extending healthy life span—from yeast to humans. Science 328, 321–326 (2010).
doi: 10.1126/science.1172539
Arantes-Oliveira, N., Berman, J. R. & Kenyon, C. Healthy animals with extreme longevity. Science 302, 611 (2003).
doi: 10.1126/science.1089169
Chiang, W. C., Ching, T. T., Lee, H. C., Mousigian, C. & Hsu, A. L. HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity. Cell 148, 322–334 (2012).
doi: 10.1016/j.cell.2011.12.019
Mesa, R. et al. HID-1, a new component of the peptidergic signaling pathway. Genetics 187, 467–483 (2011).
doi: 10.1534/genetics.110.121996
Du, W. et al. HID-1 is required for homotypic fusion of immature secretory granules during maturation. eLife 5, e18134 (2016).
doi: 10.7554/eLife.18134
Hawlena, D. & Schmitz, O. J. Herbivore physiological response to predation risk and implications for ecosystem nutrient dynamics. Proc. Natl Acad. Sci. USA 107, 15503–15507 (2010).
doi: 10.1073/pnas.1009300107
Rabasa, C. & Dickson, S. Impact of stress on metabolism and energy balance. Curr. Opin. Behav. Sci. 9, 71–77 (2016).
doi: 10.1016/j.cobeha.2016.01.011
Van Voorhies, W. A. & Ward, S. Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc. Natl Acad. Sci. USA 96, 11399–11403 (1999).
doi: 10.1073/pnas.96.20.11399
Lee, I., Hendrix, A., Kim, J., Yoshimoto, J. & You, Y. J. Metabolic rate regulates L1 longevity in C. elegans. PLoS ONE 7, e44720 (2012).
doi: 10.1371/journal.pone.0044720
Brenner, S. The genetics of Caenorhabditis elegans. Genetics 77, 71–94 (1974).
pubmed: 4366476
pmcid: 1213120
Stiernagle, T. Maintenance of C. elegans. WormBook 1–11 (2006).
Jin, X., Pokala, N. & Bargmann, C. I. Distinct circuits for the formation and retrieval of an imprinted olfactory memory. Cell 164, 632–643 (2016).
doi: 10.1016/j.cell.2016.01.007
Lionaki, E. & Tavernarakis, N. Assessing aging and senescent decline in Caenorhabditis elegans: cohort survival analysis. Methods Mol. Biol. 965, 473–484 (2013).
doi: 10.1007/978-1-62703-239-1_31
Kenyon, C., Chang, J., Gensch, E., Rudner, A. & Tabtiang, R. A C. elegans mutant that lives twice as long as wild type. Nature 366, 461–464 (1993).
doi: 10.1038/366461a0
Dorman, J. B., Albinder, B., Shroyer, T. & Kenyon, C. The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. Genetics 141, 1399–1406 (1995).
pubmed: 8601482
pmcid: 1206875
Chun, L. et al. Metabotropic GABA signalling modulates longevity in C. elegans. Nat. Commun. 6, 8828 (2015).
doi: 10.1038/ncomms9828
Swierczek, N. A., Giles, A. C., Rankin, C. H. & Kerr, R. A. High-throughput behavioral analysis in C. elegans. Nat. Methods 8, 592–598 (2011).
doi: 10.1038/nmeth.1625
Yemini, E., Kerr, R. A. & Schafer, W. R. Tracking movement behavior of multiple worms on food. Cold Spring Harb. Protoc. 2011, 1483–1487 (2011).
pubmed: 22135669
pmcid: 4874462
Edelstein, A. D. et al. Advanced methods of microscope control using μManager software. J. Biol. Methods 1, e10 (2014).
doi: 10.14440/jbm.2014.36
Hawk, J. D. et al. Integration of plasticity mechanisms within a single sensory neuron of C. elegans actuates a memory. Neuron 97, 356–367.e4 (2018).
doi: 10.1016/j.neuron.2017.12.027
Ayyadevara, S. et al. Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. Aging Cell 4, 257–271 (2005).
doi: 10.1111/j.1474-9726.2005.00168.x
Pokala, N., Liu, Q., Gordus, A. & Bargmann, C. I. Inducible and titratable silencing of Caenorhabditis elegans neurons in vivo with histamine-gated chloride channels. Proc. Natl Acad. Sci. USA 111, 2770–2775 (2014).
doi: 10.1073/pnas.1400615111