The Role of Surgery in the Management of Prolactinomas.


Journal

Neurosurgery clinics of North America
ISSN: 1558-1349
Titre abrégé: Neurosurg Clin N Am
Pays: United States
ID NLM: 9008004

Informations de publication

Date de publication:
Oct 2019
Historique:
entrez: 1 9 2019
pubmed: 1 9 2019
medline: 23 2 2020
Statut: ppublish

Résumé

Prolactinomas are the most common functional pituitary adenoma. Many prolactinomas can be treated with medication, but all patients should be evaluated at a neuroendocrine center including experienced neurosurgeons trained in transsphenoidal surgery. Surgery for prolactinomas is feasible and can be performed with low morbidity. Patients never previously treated with dopamine agonists should be considered for surgery if they have neurologic deficits, pituitary apoplexy, an uncertain diagnosis, or a significantly cystic prolactinoma. Patients previously treated with dopamine agonists should be considered for surgery in cases of intolerance or resistance. Recurrent and aggressive prolactinomas often require multimodal therapy.

Identifiants

pubmed: 31471058
pii: S1042-3680(19)30046-4
doi: 10.1016/j.nec.2019.05.010
pii:
doi:

Substances chimiques

Dopamine Agonists 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

509-514

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Daniel A Donoho (DA)

Department of Neurosurgery, Brigham and Women's Hospital, BTM 4, 60 Fenwood Road, Boston, MA 02115, USA. Electronic address: Daniel.Donoho@med.usc.edu.

Edward R Laws (ER)

Department of Neurosurgery, Brigham and Women's Hospital, BTM 4, 60 Fenwood Road, Boston, MA 02115, USA.

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Classifications MeSH