Piper diospyrifolium Kunth.: Chemical analysis and antimicrobial (intrinsic and combined) activities.
Cell viability
Escherichia coli
Fluconazole
Synergism
Virulence
Z-Carpacin
Journal
Microbial pathogenesis
ISSN: 1096-1208
Titre abrégé: Microb Pathog
Pays: England
ID NLM: 8606191
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
19
07
2019
revised:
27
08
2019
accepted:
28
08
2019
pubmed:
1
9
2019
medline:
11
3
2020
entrez:
1
9
2019
Statut:
ppublish
Résumé
The secular use of plants in popular medicine has emerged as a source for the discovery of new compounds capable of curing infections. Among microbial resistance to commercial drugs, species such as Piper diospyrifolium Kunth, which are used in popular therapy, are targets for pharmacological studies. With this in mind, antimicrobial experiments with the essential oil from the P. diospyrifolium (PDEO) species were performed and its constituents were elucidated. The oil compounds were identified by gas chromatography coupled to mass spectrometry (GC/MS). The broth microdilution method with colorimetric readings for bacterial tests (Escherichia coli and Staphylococcus aureus) and spectrophotometric readings for fungal tests (Candida albicans and Candida tropicalis), whose data were used to create a cell viability curve and calculate its IC
Identifiants
pubmed: 31472258
pii: S0882-4010(19)31296-3
doi: 10.1016/j.micpath.2019.103700
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Oils, Volatile
0
Phytochemicals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
103700Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.