Serum Serotonin as a Potential Diagnostic Marker for Hepatocellular Carcinoma.
HCC
alpha fetoprotein
biomarker
early detection
serum serotonin
Journal
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
ISSN: 1557-7465
Titre abrégé: J Interferon Cytokine Res
Pays: United States
ID NLM: 9507088
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
pubmed:
4
9
2019
medline:
12
8
2020
entrez:
4
9
2019
Statut:
ppublish
Résumé
To assess the potential role of serum serotonin level in hepatocellular carcinoma (HCC) diagnosis. A case-control study that involved 100 Egyptian adults. Subjects were divided into 4 groups: Group I: 21 patients with late-stage HCC on top of liver cirrhosis, Group II: 28 patients with early-stage HCC on top of liver cirrhosis, Group III: 26 patients with cirrhosis with no evidence of HCC, and Group IV: 25 healthy age- and sex-matched subjects were as a control group. Serum serotonin level was determined in all recruited subjects using high-performance liquid chromatography-fluorescent detection method. Alpha-fetoprotein had a statistically significant elevation in group I with a median of 1300 ng/L (195-2544 ng/L) compared to groups II and III (
Identifiants
pubmed: 31478787
doi: 10.1089/jir.2019.0088
doi:
Substances chimiques
Biomarkers, Tumor
0
Serotonin
333DO1RDJY
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM