Apolipoprotein B/AI ratio as an independent risk factor for intracranial atherosclerotic stenosis.
apolipoprotein AI
apolipoprotein B
intracranial atherosclerotic stenosis
ischemic stroke
steno-occlusion lesions
Journal
Aging
ISSN: 1945-4589
Titre abrégé: Aging (Albany NY)
Pays: United States
ID NLM: 101508617
Informations de publication
Date de publication:
03 09 2019
03 09 2019
Historique:
received:
10
06
2019
accepted:
13
08
2019
pubmed:
4
9
2019
medline:
22
9
2020
entrez:
4
9
2019
Statut:
ppublish
Résumé
To investigate the relation of higher apolipoprotein B/apolipoprotein AI (apoB/AI) ratio with the risk of suffering intracranial atherosclerotic stenosis (ICAS) in both stroke and non-stroke population, we enrolled 1138 patients with acute ischemic stroke (359 with ICAS, 779 without ICAS) and 1072 non-stroke controls (239 with ICAS, 833 without ICAS) into the study. ICAS was defined as atherosclerotic stenosis >50% or the occlusion of the several main intracranial arteries. ApoB/AI ratio of patients with ICAS was significantly higher than those of individuals without ICAS in both stroke group and non-stroke groups. Increased ratio of apoB/AI was an independent risk factor for ICAS in both stroke group (OR 2.80, 95% CI 1.45-5.42,
Identifiants
pubmed: 31479420
doi: 10.18632/aging.102216
pii: 102216
pmc: PMC6756877
doi:
Substances chimiques
Apolipoprotein A-I
0
Apolipoproteins B
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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