Risk factors for symptomatic venous thromboembolism following surgery for closed ankle fractures: A case-control study.
Adult
Age Factors
Aged
Aged, 80 and over
Ankle Fractures
/ surgery
Body Mass Index
Case-Control Studies
Cohort Studies
Comorbidity
Female
Fractures, Closed
/ surgery
Humans
Male
Middle Aged
Obesity
/ complications
Postoperative Complications
Risk Factors
Venous Thromboembolism
/ etiology
Young Adult
Ankle fracture
Case-control
Deep venous thrombosis
Lung embolism
ORIF
Risk factors
Venous thromboembolism
Journal
Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
ISSN: 1460-9584
Titre abrégé: Foot Ankle Surg
Pays: France
ID NLM: 9609647
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
18
06
2019
revised:
19
07
2019
accepted:
19
08
2019
pubmed:
5
9
2019
medline:
7
1
2021
entrez:
5
9
2019
Statut:
ppublish
Résumé
We analyzed risk factors for venous thromboembolism (VTE) within 6 months after surgery for closed ankle fractures. This was a case-control study based on data from chart review in a cohort of patients having open reduction and internal fixation (ORIF) for closed ankle fractures in two large general hospitals 2009-2011. Cases with symptomatic VTE (pulmonary embolism or deep venous thrombosis) were identified in the cohort, and additional cases of VTE were identified by computerized search of discharge diagnoses in the same hospitals in 2004-2008 and 2012-2016. In total, we identified 60 cases with VTE and compared with 240 randomly selected controls among 998 patients without VTE in the cohort. Risk factors were assessed using logistic regression analysis. Among cases, 27 (45%) had pulmonary embolism, 33 (55%) deep venous thrombosis. Those with VTE were older, had higher BMI, had more often a family history of VTE, and more often had antibiotic prophylaxis during surgery than controls. In multivariable logistic regression analysis age/10 (OR 25.75, 95%CI 3.52-188.44, p=0.001), (age/10) The odds of symptomatic VTE within 6 months of ORIF increased with increasing age and BMI, but were lower with increasing comorbidity.
Sections du résumé
BACKGROUND
BACKGROUND
We analyzed risk factors for venous thromboembolism (VTE) within 6 months after surgery for closed ankle fractures.
METHODS
METHODS
This was a case-control study based on data from chart review in a cohort of patients having open reduction and internal fixation (ORIF) for closed ankle fractures in two large general hospitals 2009-2011. Cases with symptomatic VTE (pulmonary embolism or deep venous thrombosis) were identified in the cohort, and additional cases of VTE were identified by computerized search of discharge diagnoses in the same hospitals in 2004-2008 and 2012-2016. In total, we identified 60 cases with VTE and compared with 240 randomly selected controls among 998 patients without VTE in the cohort. Risk factors were assessed using logistic regression analysis.
RESULTS
RESULTS
Among cases, 27 (45%) had pulmonary embolism, 33 (55%) deep venous thrombosis. Those with VTE were older, had higher BMI, had more often a family history of VTE, and more often had antibiotic prophylaxis during surgery than controls. In multivariable logistic regression analysis age/10 (OR 25.75, 95%CI 3.52-188.44, p=0.001), (age/10)
CONCLUSIONS
CONCLUSIONS
The odds of symptomatic VTE within 6 months of ORIF increased with increasing age and BMI, but were lower with increasing comorbidity.
Identifiants
pubmed: 31481323
pii: S1268-7731(19)30138-9
doi: 10.1016/j.fas.2019.08.006
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
681-686Informations de copyright
Copyright © 2019 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.