Visfatin Levels May be an Early Marker of Atherosclerosis in Patients with Acromegaly.
Acromegaly
/ blood
Adult
Atherosclerosis
/ blood
Biomarkers
/ blood
Blood Glucose
/ analysis
Carotid Intima-Media Thickness
Case-Control Studies
Cross-Sectional Studies
Cytokines
/ blood
Female
Follow-Up Studies
Glycated Hemoglobin
/ analysis
Human Growth Hormone
/ blood
Humans
Insulin-Like Growth Factor I
/ analysis
Male
Middle Aged
Nicotinamide Phosphoribosyltransferase
/ blood
Prognosis
Journal
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
ISSN: 1439-4286
Titre abrégé: Horm Metab Res
Pays: Germany
ID NLM: 0177722
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
pubmed:
6
9
2019
medline:
15
2
2020
entrez:
6
9
2019
Statut:
ppublish
Résumé
The purpose of the study was to compare serum visfatin levels between patients with acromegaly and healthy controls and to evaluate the relationships between visfatin levels and epicardial fat thickness (EFT), carotid intima media thickness (cIMT), and ankle brachial index (ABI). We conducted a cross-sectional case-control study of 54 patients with acromegaly (37 females and 17 males) and 34 healthy controls (22 females and 12 males). Serum visfatin was measured by ELISA. Acromegalic and control participants and those with active or controlled acromegaly were compared with respect to their serum visfatin, clinical and metabolic parameters, EFT, cIMT, and ABI. Linear correlation was used to identify associations between these parameters and visfatin in all participants. Serum visfatin and glycated hemoglobin (HbA1c) were higher in the acromegaly group than in the control group (p
Substances chimiques
Biomarkers
0
Blood Glucose
0
Cytokines
0
Glycated Hemoglobin A
0
IGF1 protein, human
0
hemoglobin A1c protein, human
0
Human Growth Hormone
12629-01-5
Insulin-Like Growth Factor I
67763-96-6
Nicotinamide Phosphoribosyltransferase
EC 2.4.2.12
nicotinamide phosphoribosyltransferase, human
EC 2.4.2.12
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
649-654Informations de copyright
© Georg Thieme Verlag KG Stuttgart · New York.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.