Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study.
Bipolar disorder
Familial high risk
Quality of life
Schizophrenia
Self-esteem
Journal
European child & adolescent psychiatry
ISSN: 1435-165X
Titre abrégé: Eur Child Adolesc Psychiatry
Pays: Germany
ID NLM: 9212296
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
05
03
2019
accepted:
30
08
2019
pubmed:
9
9
2019
medline:
5
8
2020
entrez:
9
9
2019
Statut:
ppublish
Résumé
It is well established that children with familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) have a higher risk of developing mental disorders, however, little is known of to what degree the genetic and environmental vulnerabilities affect the quality of life and self-esteem of these children. We aimed to compare the quality of life and self-esteem between children with FHR-SZ or FHR-BP and controls. We used Danish nationwide registers to retrieve a cohort of 522 7-year-old children with FHR-SZ or FHR-BP and controls. Quality of life was assessed with the 'Health-related Quality of Life Screening Instrument', KIDSCREEN-27, and the scale 'Social Acceptance (Bullying)' from the KIDSCREEN-52. Self-esteem was assessed with the self-report scale 'I think I am'. Assessors were blind to familial risk status of the children. Children with FHR-SZ displayed lower levels of the general quality of life, as well as lower scores on the 'Psychological Well-being' scale and the 'School Environment' scale of the KIDSCREEN-27 compared with controls. Both children with FHR-SZ and FHR-BP reported more bullying victimization compared with controls. Children with FHR-SZ reported lower self-esteem on the total scale of 'I think I am', as well as on the 'Skills and talents', the 'Psychological well-being', and the 'Relationships with others' subscales compared with controls. The findings of lower quality of life and self-esteem in children with FHR-SZ together with more bullying victimization in both familial high-risk groups call for studies on low risk, early intervention strategies towards this group of vulnerable children.
Identifiants
pubmed: 31494772
doi: 10.1007/s00787-019-01397-3
pii: 10.1007/s00787-019-01397-3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
849-860Subventions
Organisme : Lundbeckfonden
ID : The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) (Grant No. R102-A9118)
Organisme : Lundbeckfonden
ID : The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) (Grant No. R155-2014-1724)
Organisme : The Beatrice Surovell Haskell Fund for Child Mental Health Research of Copenhagen
ID : (Grant No. J.NR 11531)
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