Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease.

Aging / immunology Animals Antibodies / pharmacology Apoptosis Bronchoalveolar Lavage Fluid / cytology Chemotaxis, Leukocyte Cytokines / blood Cytoplasmic Granules / chemistry Endothelial Cells / metabolism Eosinophils / drug effects Intercellular Adhesion Molecule-1 / physiology Interleukin-5 / immunology Lung Diseases, Obstructive / metabolism Mice Mice, Inbred C57BL Mice, Transgenic Mucus / metabolism Pulmonary Eosinophilia / drug therapy Receptors, Interleukin-1 Type I / deficiency Signal Transduction Specific Pathogen-Free Organisms
IL-1 eosinophil migration type 2 inflammation

Journal

American journal of respiratory cell and molecular biology
ISSN: 1535-4989
Titre abrégé: Am J Respir Cell Mol Biol
Pays: United States
ID NLM: 8917225

Informations de publication

Date de publication:
03 2020
Historique:
pubmed: 10 9 2019
medline: 28 7 2020
entrez: 10 9 2019
Statut: ppublish

Résumé

Previous studies demonstrated spontaneous type 2 airway inflammation with eosinophilia in juvenile

Identifiants

DOI: 10.1165/rcmb.2018-0359OC PMID: 31499011
pubmed: 31499011
doi: 10.1165/rcmb.2018-0359OC
doi:

Substances chimiques

Antibodies 0
Cytokines 0
IL1R1 protein, mouse 0
Interleukin-5 0
Receptors, Interleukin-1 Type I 0
Intercellular Adhesion Molecule-1 126547-89-5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

300-309

Commentaires et corrections

Type : CommentIn

Auteurs

Ryan Brown (R)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Michelle Paulsen (M)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Simone Schmidt (S)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Jolanthe Schatterny (J)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Angela Frank (A)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Stephanie Hirtz (S)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Rebecca Delaney (R)

Airway Innate Immunity Research Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland.

Declan Doherty (D)

Airway Innate Immunity Research Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland.

Matthias Hagner (M)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.

Cliff Taggart (C)

Airway Innate Immunity Research Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland.

Sinéad Weldon (S)

Airway Innate Immunity Research Group, Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland.

Marcus A Mall (MA)

Department of Translational Pulmonology, Translational Lung Research Centre Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany.
Department of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany; and.
Berlin Institute of Health, Berlin, Germany.
ORCID: 0000-0002-4057-2199

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Vieillissement › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Techniques d'investigation › Irrigation thérapeutique › Lavage bronchoalvéolaire › Liquide de lavage bronchoalvéolaire › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Chimiotaxie des leucocytes › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Granulations cytoplasmiques › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Granulocytes › Granulocytes éosinophiles › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Molécule-1 d'adhérence intercellulaire › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-5 › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Maladies pulmonaires › Bronchopneumopathies obstructives › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Liquides et sécrétions biologiques › Sécrétions corporelles › Mucus › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Troubles leucocytaires › Éosinophilie › Syndrome hyperéosinophilique › Poumon éosinophile › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux interleukines › Récepteurs à l'interleukine-1 › Récepteur à l'interleukine-1 de type I › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Lack of IL-1 Receptor Signaling Reduces...
questionsmedicales.fr › Phénomènes microbiologiques › Axénie › Organismes exempts d'organismes pathogènes spécifiques › Lack of IL-1 Receptor Signaling Reduces...