How Cells Handle DNA Breaks during Mitosis: Detection, Signaling, Repair, and Fate Choice.
DNA damage
DNA repair
cancer
cell fate
mitosis
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
07 09 2019
07 09 2019
Historique:
received:
06
08
2019
revised:
01
09
2019
accepted:
05
09
2019
entrez:
11
9
2019
pubmed:
11
9
2019
medline:
12
6
2020
Statut:
epublish
Résumé
Mitosis is controlled by a complex series of signaling pathways but mitotic control following DNA damage remains poorly understood. Effective DNA damage sensing and repair is integral to survival but is largely thought to occur primarily in interphase and be repressed during mitosis due to the risk of telomere fusion. There is, however, increasing evidence to suggest tight control of mitotic progression in the incidence of DNA damage, whether induced in mitotic cells or having progressed from failed interphase checkpoints. Here we will discuss what is known to date about signaling pathways controlling mitotic progression and resulting cell fate in the incidence of mitotic DNA damage.
Identifiants
pubmed: 31500247
pii: cells8091049
doi: 10.3390/cells8091049
pmc: PMC6770852
pii:
doi:
Substances chimiques
Intracellular Signaling Peptides and Proteins
0
DNA
9007-49-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NCI NIH HHS
ID : R01 CA178162
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM135301
Pays : United States
Références
PLoS Genet. 2008 Feb 29;4(2):e1000015
pubmed: 18454191
PLoS Genet. 2014 Aug 28;10(8):e1004563
pubmed: 25166505
Cell. 2007 Jan 12;128(1):101-14
pubmed: 17218258
J Cell Sci. 2003 Dec 1;116(Pt 23):4763-76
pubmed: 14600262
Curr Biol. 2005 Feb 22;15(4):334-9
pubmed: 15723794
Nat Cell Biol. 2011 Mar;13(3):243-53
pubmed: 21317883
Cell Death Differ. 2019 Jan;26(2):332-347
pubmed: 29786074
Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4612-E4620
pubmed: 28533362
Genes Dev. 2017 Jan 1;31(1):34-45
pubmed: 28130345
FASEB J. 2017 Oct;31(10):4295-4304
pubmed: 28626028
Curr Biol. 2006 Oct 10;16(19):1950-5
pubmed: 16934469
J Cell Biol. 2015 Aug 17;210(4):565-82
pubmed: 26283799
EMBO J. 2007 Jul 25;26(14):3397-409
pubmed: 17599064
Oncogene. 2009 Aug 6;28(31):2806-20
pubmed: 19503101
Mol Cell. 2006 Aug 4;23(3):307-18
pubmed: 16885021
Nucleic Acids Res. 2012 Jan;40(1):196-205
pubmed: 21911360
Cell. 2014 Dec 18;159(7):1549-62
pubmed: 25525874
Mol Cell. 2012 Sep 14;47(5):681-93
pubmed: 22854598
Mediators Inflamm. 2015;2015:146282
pubmed: 26491220
J Biol Chem. 2014 Mar 21;289(12):8182-93
pubmed: 24509855
Science. 2014 Apr 11;344(6180):189-93
pubmed: 24652939
Cell. 2015 Jul 16;162(2):425-440
pubmed: 26186194
Dev Cell. 2007 Feb;12(2):247-60
pubmed: 17276342
Nature. 2018 Jan 25;553(7689):467-472
pubmed: 29342134
J Cell Biol. 2017 Jun 5;216(6):1795-1810
pubmed: 28432080
Nature. 2017 Aug 24;548(7668):461-465
pubmed: 28738408
Cell Cycle. 2015;14(2):219-31
pubmed: 25607646
Oncogene. 2009 Sep 3;28(35):3093-6
pubmed: 19581929
Nature. 2017 Aug 24;548(7668):466-470
pubmed: 28759889
Cell. 2014 Dec 18;159(7):1563-77
pubmed: 25525875
PLoS One. 2014 May 07;9(5):e97028
pubmed: 24806815
Cell. 2008 May 30;133(5):864-77
pubmed: 18510930
Dev Cell. 2015 Aug 24;34(4):466-74
pubmed: 26256213
Mol Cell. 2013 Dec 12;52(5):667-78
pubmed: 24239288
Oncogene. 2004 Aug 26;23(39):6548-58
pubmed: 15221012
Cell Death Differ. 2012 Jan;19(1):51-7
pubmed: 22075987
Nature. 2003 Feb 27;421(6926):961-6
pubmed: 12607005
Curr Biol. 2002 Oct 29;12(21):1797-806
pubmed: 12419179
EMBO J. 2013 Oct 16;32(20):2661-71
pubmed: 24065128
Mol Cell Oncol. 2015 Jul 06;3(3):e1059921
pubmed: 27314076
Annu Rev Genet. 2007;41:169-92
pubmed: 17608616
FASEB J. 2014 Dec;28(12):5250-61
pubmed: 25205741
J Biol Chem. 2011 Jun 17;286(24):21173-9
pubmed: 21525009
J Cell Biol. 2016 Jul 18;214(2):155-66
pubmed: 27432897
Nat Cell Biol. 2017 Sep;19(9):1061-1070
pubmed: 28759028
J Cell Biol. 1999 Feb 22;144(4):589-601
pubmed: 10037783
Nat Cell Biol. 2000 Sep;2(9):672-6
pubmed: 10980711
Mol Cell. 2006 Aug 4;23(3):319-29
pubmed: 16885022
Cell Cycle. 2009 Jul 1;8(13):1997-2001
pubmed: 19502806
Chromosoma. 2004 Jun;112(8):389-97
pubmed: 15156327
J Biol Chem. 2007 Nov 2;282(44):32053-64
pubmed: 17827148
DNA Repair (Amst). 2014 Mar;15:54-9
pubmed: 24462468
Carcinogenesis. 2014 Sep;35(9):2007-13
pubmed: 24728176
J Cell Biol. 1997 Jan 27;136(2):345-54
pubmed: 9015305
Nat Cell Biol. 2016 Dec 23;19(1):1-9
pubmed: 28008184
Nat Cell Biol. 2009 Mar;11(3):278-85
pubmed: 19182792
Radiat Res. 1991 Dec;128(3):251-7
pubmed: 1961921
Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10079-E10088
pubmed: 30297404
Nucleus. 2013 May-Jun;4(3):160-5
pubmed: 23644379
PLoS Biol. 2010 Jan 26;8(1):e1000287
pubmed: 20126263
Curr Biol. 2015 Oct 19;25(20):R1002-18
pubmed: 26485365
Science. 2004 May 7;304(5672):843-6
pubmed: 15073321
Nature. 2015 Dec 10;528(7581):286-90
pubmed: 26633632
Cell Cycle. 2009 Oct 15;8(20):3379-83
pubmed: 19806024
Genetics. 1941 Mar;26(2):234-82
pubmed: 17247004
Mol Cell. 2019 May 2;74(3):571-583.e8
pubmed: 30898438
J Biol Chem. 2009 Dec 4;284(49):33939-48
pubmed: 19826003
Genes Chromosomes Cancer. 2007 Jun;46(6):522-31
pubmed: 17366618
Genes Dev. 1999 Aug 1;13(15):1936-49
pubmed: 10444592
Nat Cell Biol. 2001 Jan;3(1):E3-6
pubmed: 11146636
J Cell Biol. 2010 Jul 26;190(2):197-207
pubmed: 20660628
Nature. 2017 Oct 19;550(7676):402-406
pubmed: 28976970
Cell. 2010 Jan 22;140(2):235-45
pubmed: 20141837
Mol Cell. 2015 Jun 4;58(5):767-79
pubmed: 25936804
Nat Cell Biol. 2003 Dec;5(12):1090-4
pubmed: 14634663