Diffusion weighted magnetic resonance imaging of pre and post treatment nasopharyngeal carcinoma.
Apparent diffusion coefficient
Cancer detection
Diffused weighted magnetic resonance imaging
Nasopharyngeal carcinoma
Journal
Surgical oncology
ISSN: 1879-3320
Titre abrégé: Surg Oncol
Pays: Netherlands
ID NLM: 9208188
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
22
12
2018
revised:
28
06
2019
accepted:
22
07
2019
entrez:
11
9
2019
pubmed:
11
9
2019
medline:
11
2
2020
Statut:
ppublish
Résumé
To evaluate the utility of different Apparent Diffusion Coefficient (ADC) values on Diffused Weighted Magnetic Resonance Imaging (DW-MRI) for nasopharyngeal carcinoma (NPC). A retrospective cohort study in a single tertiary medical center. The study group consists of patients with pathology proven NPC that underwent DW-MRI prior or/and following a non-surgical chemo radiation treatment between the years 2007 and 2017. ADC thresholds were analyzed and compared for primary (pre-treatment) and expected post-irradiation NPC cases and healthy controls. We recruited 144 patients who underwent 195 MRI's for NPC. 25 DW-MRI were performed before (primary, active NPC) and 56 following (no residual NPC) treatment. 45 out of 225 patients who had brain DW-MRI for other reasons (control group) had measurable nasopharynx tissue (N = 33, adjusted for age and gender). The mean ADC of NPC prior to treatment (0.69 ± 0.13 × 10 ADC levels have distinct values in newly diagnosed and follow up of NPC.
Identifiants
pubmed: 31500774
pii: S0960-7404(18)30510-3
doi: 10.1016/j.suronc.2019.07.005
pii:
doi:
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
122-125Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.