White matter microstructure mediates the association between physical fitness and cognition in healthy, young adults.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
09 09 2019
09 09 2019
Historique:
received:
13
06
2019
accepted:
19
08
2019
entrez:
11
9
2019
pubmed:
11
9
2019
medline:
3
11
2020
Statut:
epublish
Résumé
We aimed to extend our knowledge on the relationship between physical fitness (PF) and both white matter microstructure and cognition through in-depth investigation of various cognitive domains while accounting for potentially relevant nuisance covariates in a well-powered sample. To this end, associations between walking endurance, diffusion-tensor-imaging (DTI) based measures of fractional anisotropy (FA) within brain white matter and cognitive measures included in the NIH Toolbox Cognition Battery were investigated in a sample of n = 1206 healthy, young adults (mean age = 28.8; 45.5% male) as part of the human connectome project. Higher levels of endurance were associated with widespread higher FA (p
Identifiants
pubmed: 31501448
doi: 10.1038/s41598-019-49301-y
pii: 10.1038/s41598-019-49301-y
pmc: PMC6733843
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
12885Subventions
Organisme : NIMH NIH HHS
ID : U54 MH091657
Pays : United States
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