The Improvement in 1-Year Survival Rate of Patients with Hepatocellular Carcinoma BCLC Stage A and B after the Implementation of Comprehensive Management.
Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular
/ diagnosis
Comprehensive Health Care
/ methods
Early Detection of Cancer
Female
Health Plan Implementation
Humans
Indonesia
/ epidemiology
Kaplan-Meier Estimate
Liver Neoplasms
/ diagnosis
Male
Mass Screening
/ organization & administration
Middle Aged
Neoplasm Staging
Patient Education as Topic
/ organization & administration
Program Evaluation
Retrospective Studies
Social Media
Survival Rate
Comprehensive management
Curative
Hepatectomy
Hepatocellular carcinoma
Radiofrequency ablation
Surveillance
Survival rate
Journal
Journal of gastrointestinal cancer
ISSN: 1941-6636
Titre abrégé: J Gastrointest Cancer
Pays: United States
ID NLM: 101479627
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
pubmed:
11
9
2019
medline:
1
4
2021
entrez:
11
9
2019
Statut:
ppublish
Résumé
The previous study showed lack of improvement in survival rate of hepatocellular carcinoma (HCC) patients in 2013-2014 period compared to 1998-1999 period in Indonesia due to late diagnosis. Comprehensive management of HCC has been implemented since 2015 in Cipto Mangunkusumo National General Hospital. This aims to provide better screening and surveillance in HCC patients and prioritizing of more proactive approach, such as online patient's group discussion and social media education. To compare the survival rates in HCC BCLC stage A and B before and after the implementation of comprehensive management. A retrospective study design was conducted in this study. We compared the database of HCC BCLC A and B patients between the 2015-2017 period and the 2013-2014 period. Clinical parameters, modality of treatment, and 1-year survival rate were analyzed. A total of 50 patients from 2013 to 2014 period and 143 patients from 2015 to 2017 period were included in this study. After the implementation of comprehensive management, the number of patients detected in BCLC class A increased significantly (p = 0.003). In 2015-2017 period, the number of patients that received curative treatment increased significantly (p = 0.018). The 1-year survival rate of the 2015-2017 group and the 2013-2014 group was 73.9% and 47.9%, respectively, with p value 0.002. The 1-year survival rate of BCLC A and BCLC B HCC patients in Cipto Mangunkusumo National Hospital improved significantly after the implementation of comprehensive management of HCC in 2015.
Sections du résumé
BACKGROUND
BACKGROUND
The previous study showed lack of improvement in survival rate of hepatocellular carcinoma (HCC) patients in 2013-2014 period compared to 1998-1999 period in Indonesia due to late diagnosis. Comprehensive management of HCC has been implemented since 2015 in Cipto Mangunkusumo National General Hospital. This aims to provide better screening and surveillance in HCC patients and prioritizing of more proactive approach, such as online patient's group discussion and social media education.
AIM
OBJECTIVE
To compare the survival rates in HCC BCLC stage A and B before and after the implementation of comprehensive management.
METHODS
METHODS
A retrospective study design was conducted in this study. We compared the database of HCC BCLC A and B patients between the 2015-2017 period and the 2013-2014 period. Clinical parameters, modality of treatment, and 1-year survival rate were analyzed.
RESULTS
RESULTS
A total of 50 patients from 2013 to 2014 period and 143 patients from 2015 to 2017 period were included in this study. After the implementation of comprehensive management, the number of patients detected in BCLC class A increased significantly (p = 0.003). In 2015-2017 period, the number of patients that received curative treatment increased significantly (p = 0.018). The 1-year survival rate of the 2015-2017 group and the 2013-2014 group was 73.9% and 47.9%, respectively, with p value 0.002.
CONCLUSIONS
CONCLUSIONS
The 1-year survival rate of BCLC A and BCLC B HCC patients in Cipto Mangunkusumo National Hospital improved significantly after the implementation of comprehensive management of HCC in 2015.
Identifiants
pubmed: 31502104
doi: 10.1007/s12029-019-00298-7
pii: 10.1007/s12029-019-00298-7
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM