Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance.


Journal

Cancer research
ISSN: 1538-7445
Titre abrégé: Cancer Res
Pays: United States
ID NLM: 2984705R

Informations de publication

Date de publication:
01 Nov 2019
Historique:
received: 11 01 2019
revised: 17 05 2019
accepted: 06 09 2019
pubmed: 12 9 2019
medline: 29 5 2020
entrez: 12 9 2019
Statut: ppublish

Résumé

Colorectal cancer is characterized by well-known genetic defects and approximately 50% of cases harbor oncogenic

Identifiants

pubmed: 31506332
pii: 0008-5472.CAN-19-0145
doi: 10.1158/0008-5472.CAN-19-0145
doi:

Substances chimiques

JAG1 protein, human 0
Jagged-1 Protein 0
KRAS protein, human 0
ADAM17 Protein EC 3.4.24.86
ADAM17 protein, human EC 3.4.24.86
Proto-Oncogene Proteins p21(ras) EC 3.6.5.2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5575-5586

Informations de copyright

©2019 American Association for Cancer Research.

Auteurs

Maria Pelullo (M)

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.

Francesca Nardozza (F)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Sabrina Zema (S)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Roberta Quaranta (R)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Carmine Nicoletti (C)

Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Unit of Histology and Medical Embryology, Sapienza University, Rome, Italy.

Zein Mersini Besharat (ZM)

Department of Experimental Medicine, Sapienza University, Rome, Italy.

Maria Pia Felli (MP)

Department of Experimental Medicine, Sapienza University, Rome, Italy.

Bruna Cerbelli (B)

Department of Radiological, Oncological and Pathological Sciences, Sapienza University, Rome, Italy.

Giulia d'Amati (G)

Department of Radiological, Oncological and Pathological Sciences, Sapienza University, Rome, Italy.

Rocco Palermo (R)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Carlo Capalbo (C)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Claudio Talora (C)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Lucia Di Marcotullio (L)

Department of Molecular Medicine, Sapienza University, Laboratory affiliated to Istituto Pasteur Italia, Italy.

Giuseppe Giannini (G)

Department of Molecular Medicine, Sapienza University, Laboratory affiliated to Istituto Pasteur Italia, Italy.

Saula Checquolo (S)

Department of Medico-Surgical Sciences and Biotechnology, Sapienza University, Latina, Italy. diana.bellavia@uniroma1.it saula.checquolo@uniroma1.it.

Isabella Screpanti (I)

Department of Molecular Medicine, Sapienza University, Rome, Italy.

Diana Bellavia (D)

Department of Molecular Medicine, Sapienza University, Rome, Italy. diana.bellavia@uniroma1.it saula.checquolo@uniroma1.it.

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Classifications MeSH