Methacrylated gelatin hydrogels as corneal stroma substitutes:

Animals Biocompatible Materials / chemistry Cell Line Cell Survival Corneal Keratocytes / cytology Corneal Stroma / chemistry Gelatin / chemistry Humans Hydrogels / chemistry Methacrylates / chemistry Rabbits Tissue Engineering Tissue Scaffolds / chemistry
None Corneal stroma engineering GelMA hydrogels New Zealand rabbits

Journal

Journal of biomaterials science. Polymer edition
ISSN: 1568-5624
Titre abrégé: J Biomater Sci Polym Ed
Pays: England
ID NLM: 9007393

Informations de publication

Date de publication:
12 2019
Historique:
pubmed: 12 9 2019
medline: 16 7 2020
entrez: 12 9 2019
Statut: ppublish

Résumé

Methacrylated gelatin (GelMA) hydrogels were prepared to serve as corneal stroma equivalents. They were highly transparent (ca. 95% at 700 nm), mechanically strong and withstood handling and had high human corneal keratocyte viability (98%) after 21 days of culture period. In order to test the

Identifiants

DOI: 10.1080/09205063.2019.1666236 PMID: 31507241
pubmed: 31507241
doi: 10.1080/09205063.2019.1666236
doi:

Substances chimiques

Biocompatible Materials 0
Hydrogels 0
Methacrylates 0
Gelatin 9000-70-8

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1803-1821

Auteurs

Cemile Kilic Bektas (C)

Departments of Biological Sciences, Middle East Technical University (METU) , Ankara , Turkey.
Department of Biotechnology, Middle East Technical University (METU) , Ankara , Turkey.
BIOMATEN, METU Center of Excellence in Biomaterials and Tissue Engineering , Ankara , Turkey.
ORCID: 0000-0003-1565-6304

Ayse Burcu (A)

Eye Clinic, University of Health Sciences, Ankara Training and Research Hospital , Ankara , Turkey.

Gokhan Gedikoglu (G)

Department of Medical Pathology, Hacettepe University , Ankara , Turkey.

Hande H Telek (HH)

Eye Clinic, Beytepe Murat Erdi Eker State Hospital , Ankara , Turkey.

Firdevs Ornek (F)

Eye Clinic, University of Health Sciences, Ankara Training and Research Hospital , Ankara , Turkey.

Vasif Hasirci (V)

Departments of Biological Sciences, Middle East Technical University (METU) , Ankara , Turkey.
Department of Biotechnology, Middle East Technical University (METU) , Ankara , Turkey.
BIOMATEN, METU Center of Excellence in Biomaterials and Tissue Engineering , Ankara , Turkey.
Department of Medical Engineering, Acıbadem Mehmet Ali Aydınlar University , İstanbul , Turkey.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Matériaux biocompatibles › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Kératocytes cornéens › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Organes des sens › Oeil › Pôle antérieur du bulbe oculaire › Cornée › Stroma de la cornée › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Gélatine › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Acrylates › Méthacrylates › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Lagomorpha › Lapins › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Ingénierie tissulaire › Methacrylated gelatin hydrogels as corneal...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Structures d'échafaudage tissulaires › Methacrylated gelatin hydrogels as corneal...