OATP1B3-1B7, a novel organic anion transporting polypeptide, is modulated by FXR ligands and transports bile acids.
Antineoplastic Agents
/ pharmacology
Bile Acids and Salts
/ physiology
Biological Transport
/ physiology
Gene Expression Regulation
Gene Regulatory Networks
/ physiology
HeLa Cells
Hep G2 Cells
Humans
Isoxazoles
/ pharmacology
Organic Anion Transporters
/ genetics
Receptors, Cytoplasmic and Nuclear
/ agonists
Solute Carrier Organic Anion Transporter Family Member 1B3
/ genetics
Solute Carrier Proteins
/ genetics
Transcription Factors
Transcriptional Activation
LST-3TM12
OATP1B3-1B7
SLCO1B3
SLCO1B7
farnesoid X receptor
Journal
American journal of physiology. Gastrointestinal and liver physiology
ISSN: 1522-1547
Titre abrégé: Am J Physiol Gastrointest Liver Physiol
Pays: United States
ID NLM: 100901227
Informations de publication
Date de publication:
01 12 2019
01 12 2019
Historique:
pubmed:
12
9
2019
medline:
9
4
2020
entrez:
12
9
2019
Statut:
ppublish
Résumé
Organic anion transporting polypeptide (OATP) 1B3-1B7 (LST-3TM12) is a member of the OATP1B [solute carrier organic anion transporter (
Identifiants
pubmed: 31509437
doi: 10.1152/ajpgi.00330.2018
doi:
Substances chimiques
Antineoplastic Agents
0
Bile Acids and Salts
0
Isoxazoles
0
Organic Anion Transporters
0
Receptors, Cytoplasmic and Nuclear
0
SLCO1B3 protein, human
0
SLCO1B7 protein, human
0
Solute Carrier Organic Anion Transporter Family Member 1B3
0
Solute Carrier Proteins
0
Transcription Factors
0
farnesoid X-activated receptor
0C5V0MRU6P
GW 4064
SR225WUZ0H
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM