Enamel peptides reveal the sex of the Late Antique 'Lovers of Modena'.

Amelogenin / genetics Dental Enamel / metabolism Dental Enamel Proteins / genetics Female Humans Italy Male Paleontology / methods Peptide Fragments / analysis Polymerase Chain Reaction Sex Determination Analysis / methods

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
11 09 2019
Historique:
received: 13 02 2019
accepted: 07 08 2019
entrez: 13 9 2019
pubmed: 13 9 2019
medline: 5 11 2020
Statut: epublish

Résumé

Recent work has disclosed the critical role played by enamel peptides in sex classification of old skeletal remains. In particular, protein AMELY (amelogenin isoform Y) is present in the enamel dental tissue of male individuals only, while AMELX (isoform X) can be found in both sexes. AMELY can be easily detected by LC-MS/MS in the ion extracted chromatograms of the SM

Identifiants

DOI: 10.1038/s41598-019-49562-7 PMID: 31511583 PMC: PMC6739468
pubmed: 31511583
doi: 10.1038/s41598-019-49562-7
pii: 10.1038/s41598-019-49562-7
pmc: PMC6739468
doi:

Substances chimiques

AMELX protein, human 0
Amelogenin 0
Dental Enamel Proteins 0
Peptide Fragments 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

13130

Références

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Auteurs

Federico Lugli (F)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy. federico.lugli6@unibo.it.
Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy. federico.lugli6@unibo.it.
ORCID: 0000-0002-5642-2216

Giulia Di Rocco (G)

Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy. giulia.dirocco@unimore.it.

Antonino Vazzana (A)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Filippo Genovese (F)

Centro Interdipartimentale Grandi Strumenti, University of Modena and Reggio Emilia, Via Campi 213/A, 41125, Modena, Italy.

Diego Pinetti (D)

Centro Interdipartimentale Grandi Strumenti, University of Modena and Reggio Emilia, Via Campi 213/A, 41125, Modena, Italy.

Elisabetta Cilli (E)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.
ORCID: 0000-0003-0407-267X

Maria Cristina Carile (MC)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.
ORCID: 0000-0002-8873-138X

Sara Silvestrini (S)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Gaia Gabanini (G)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Simona Arrighi (S)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.
ORCID: 0000-0003-0168-8639

Laura Buti (L)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Eugenio Bortolini (E)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Anna Cipriani (A)

Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
Lamont-Doherty Earth Observatory, Columbia University, Palisades, New York, USA.
ORCID: 0000-0001-8457-0147

Carla Figus (C)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Giulia Marciani (G)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Gregorio Oxilia (G)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Matteo Romandini (M)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.

Rita Sorrentino (R)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.
Department of Biological, Geological and Environmental Sciences, University of Bologna, 40126, Bologna, Italy.
ORCID: 0000-0002-6529-7250

Marco Sola (M)

Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.

Stefano Benazzi (S)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121, Ravenna, Italy.
Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de l'émail dentaire › Amélogénine › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Système stomatognathique › Bouche › Denture › Composants dentaires › Émail dentaire › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de l'émail dentaire › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Régions géographiques › Europe › Italie › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Sciences sociales › Anthropologie › Anthropologie anatomique › Paléontologie › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Fragments peptidiques › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Techniques d'amplification d'acides nucléiques › Réaction de polymérisation en chaîne › Enamel peptides reveal the sex of the Late...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse cytogénétique › Détermination du sexe › Enamel peptides reveal the sex of the Late...