Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.


Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
13 09 2019
Historique:
received: 04 01 2019
revised: 02 07 2019
accepted: 04 08 2019
entrez: 14 9 2019
pubmed: 14 9 2019
medline: 27 3 2020
Statut: ppublish

Résumé

Mitochondrial ribosomes (mitoribosomes) are large ribonucleoprotein complexes that synthesize proteins encoded by the mitochondrial genome. An extensive cellular machinery responsible for ribosome assembly has been described only for eukaryotic cytosolic ribosomes. Here we report that the assembly of the small mitoribosomal subunit in

Identifiants

pubmed: 31515389
pii: 365/6458/1144
doi: 10.1126/science.aaw5570
doi:

Substances chimiques

Mitochondrial Proteins 0
RNA, Ribosomal 0
Ribosomal Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1144-1149

Subventions

Organisme : Swiss National Science Foundation
Pays : Switzerland

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Auteurs

Martin Saurer (M)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

David J F Ramrath (DJF)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

Moritz Niemann (M)

Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.

Salvatore Calderaro (S)

Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.

Céline Prange (C)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

Simone Mattei (S)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

Alain Scaiola (A)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

Alexander Leitner (A)

Department of Biology, Institute of Molecular Systems Biology, Otto-Stern-Weg 3, ETH Zurich, CH-8093 Zurich, Switzerland.

Philipp Bieri (P)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

Elke K Horn (EK)

Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.

Marc Leibundgut (M)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

Daniel Boehringer (D)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.

André Schneider (A)

Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. andre.schneider@dcb.unibe.ch ban@mol.biol.ethz.ch.

Nenad Ban (N)

Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland. andre.schneider@dcb.unibe.ch ban@mol.biol.ethz.ch.

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Classifications MeSH