Terminal Effector CD8 T Cells Defined by an IKZF2

Adolescent Adult Antibody-Dependent Cell Cytotoxicity / genetics CD8-Positive T-Lymphocytes / immunology Cell Differentiation / immunology Cohort Studies Female HIV Infections / immunology HIV-1 / immunology Humans Ikaros Transcription Factor / immunology Male Middle Aged Prospective Studies Receptors, IgG / genetics Receptors, Interleukin-7 / immunology Young Adult

Journal

Journal of immunology (Baltimore, Md. : 1950)

ISSN: 1550-6606

Titre abrégé: J Immunol

Pays: United States

ID NLM: 2985117R

Informations de publication

Date de publication:
15 10 2019

Historique:

received: 11 04 2019

accepted: 20 08 2019

pubmed: 15 9 2019

medline: 23 5 2020

entrez: 15 9 2019

Statut: ppublish

Résumé

HIV-1 infection expands large populations of late-stage differentiated CD8 T cells that may persist long after viral escape from TCR recognition. In this study, we investigated whether such CD8 T cell populations can perform unconventional innate-like antiviral effector functions. Chronic untreated HIV-1 infection was associated with elevated numbers of CD45RA

Identifiants

DOI: 10.4049/jimmunol.1900422 PMID: 31519862 PMC: PMC6778306

pubmed: 31519862

pii: jimmunol.1900422

doi: 10.4049/jimmunol.1900422

pmc: PMC6778306

mid: NIHMS1538270

doi:

Substances chimiques

FCGR3A protein, human 0

IKZF2 protein, human 0

Receptors, IgG 0

Receptors, Interleukin-7 0

Ikaros Transcription Factor 148971-36-2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

Pagination

2210-2221

Subventions

Organisme : NIAID NIH HHS

ID : Y01 AI002642-12

Pays : United States

Informations de copyright

Références

J Virol. 2016 Mar 28;90(8):4005-4016

pubmed: 26842474

J Virol. 2014 Nov;88(21):12895-906

pubmed: 25165110

Immunity. 2008 Dec 19;29(6):1009-21

pubmed: 19062316

PLoS Pathog. 2017 Jul 31;13(7):e1006510

pubmed: 28759651

Cytometry A. 2011 Feb;79(2):167-74

pubmed: 21265010

PLoS One. 2016 Jan 05;11(1):e0146196

pubmed: 26730706

J Exp Med. 2005 Oct 3;202(7):1001-12

pubmed: 16203869

Nature. 2001 Mar 1;410(6824):106-11

pubmed: 11242051

Sci Rep. 2017 Oct 4;7(1):12655

pubmed: 28978939

PLoS One. 2014 Feb 04;9(2):e87572

pubmed: 24504509

Cell Rep. 2016 Jul 12;16(2):379-391

pubmed: 27373165

J Virol. 2012 Jun;86(12):6835-46

pubmed: 22514337

Sci Transl Med. 2015 Apr 8;7(282):282ra48

pubmed: 25855494

J Virol. 1994 Sep;68(9):6103-10

pubmed: 8057491

J Immunol. 1983 Oct;131(4):1789-96

pubmed: 6225799

J Immunol. 1989 Apr 1;142(7):2359-64

pubmed: 2784461

Science. 2016 May 20;352(6288):997-1001

pubmed: 27199429

Blood. 2006 Jan 1;107(1):159-66

pubmed: 16150947

J Acquir Immune Defic Syndr. 2017 Jul 1;75(3):345-353

pubmed: 28346319

Nat Commun. 2016 Mar 03;7:10844

pubmed: 26936020

J Immunol Methods. 2013 May 31;391(1-2):133-45

pubmed: 23500781

Front Immunol. 2014 May 14;5:217

pubmed: 24860576

Mucosal Immunol. 2016 Nov;9(6):1584-1595

pubmed: 26883728

Nat Rev Immunol. 2008 Apr;8(4):247-58

pubmed: 18323851

J Exp Med. 2006 Oct 2;203(10):2281-92

pubmed: 16954372

Curr HIV Res. 2017;15(3):202-215

pubmed: 28322167

N Engl J Med. 2012 Apr 5;366(14):1275-86

pubmed: 22475592

J Immunol. 2008 Apr 15;180(8):5327-34

pubmed: 18390714

J Clin Invest. 2013 Jan;123(1):380-93

pubmed: 23221345

Eur J Immunol. 2019 May;49(5):694-708

pubmed: 30883723

Lancet Infect Dis. 2012 Jan;12(1):19-26

pubmed: 21975269

J Acquir Immune Defic Syndr. 2006 Dec 1;43(4):440-5

pubmed: 16980909

J Virol. 2009 Jan;83(1):329-35

pubmed: 18945778

Nature. 2006 Sep 21;443(7109):350-4

pubmed: 16921384

BMC Bioinformatics. 2017 Mar 2;18(1):142

pubmed: 28249561

Cytometry A. 2011 Aug;79(8):603-12

pubmed: 21735545

J Exp Med. 2009 Jun 8;206(6):1253-72

pubmed: 19487423

Nat Med. 2006 Oct;12(10):1198-202

pubmed: 16917489

Immunol Today. 2000 Dec;21(12):611-4

pubmed: 11114420

Science. 2016 May 20;352(6288):1001-4

pubmed: 27199430

Sci Immunol. 2018 Nov 9;3(29):

pubmed: 30413420

J Immunother. 2011 Sep;34(7):542-9

pubmed: 21760529

J Exp Med. 1994 Sep 1;180(3):779-82

pubmed: 7520471

Nat Immunol. 2002 Nov;3(11):1061-8

pubmed: 12368910

Blood. 1989 May 15;73(7):1909-14

pubmed: 2785419

J Infect Dis. 2008 Mar 1;197(5):707-13

pubmed: 18266607

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5980-E5989

pubmed: 29895693

Nature. 1987 Jul 23-29;328(6128):345-8

pubmed: 3496541

Blood. 2006 Jun 15;107(12):4781-9

pubmed: 16467198

J Immunol. 2008 Sep 15;181(6):4219-28

pubmed: 18768879

Nature. 1988 Dec 1;336(6198):484-7

pubmed: 2461519

Clin Vaccine Immunol. 2010 Jun;17(6):910-8

pubmed: 20200187

Nat Commun. 2018 Mar 23;9(1):1212

pubmed: 29572470

PLoS One. 2011 Apr 19;6(4):e18779

pubmed: 21526194

Nature. 1987 Jul 23-29;328(6128):348-51

pubmed: 3496542

J Exp Med. 1989 Aug 1;170(2):481-97

pubmed: 2526846

Cell. 2017 Aug 10;170(4):637-648.e10

pubmed: 28757252

Annu Rev Immunol. 2001;19:275-90

pubmed: 11244038

Cell. 2015 Nov 5;163(4):988-98

pubmed: 26544943

Proc Natl Acad Sci U S A. 1988 Nov;85(22):8638-42

pubmed: 2460873

J Virol. 1994 Jul;68(7):4650-5

pubmed: 8207839

Sci Transl Med. 2014 Mar 19;6(228):228ra38

pubmed: 24648341

Front Immunol. 2019 Apr 10;10:735

pubmed: 31024562

Nat Commun. 2019 Feb 8;10(1):687

pubmed: 30737409

J Immunol. 2013 Mar 1;190(5):2150-8

pubmed: 23338234

Immunol Today. 1993 May;14(5):227-31

pubmed: 8517922

AIDS Res Hum Retroviruses. 2002 Nov 20;18(17):1281-90

pubmed: 12487816