Occupationally Related Nickel Reactions: A Retrospective Analysis of the North American Contact Dermatitis Group Data 1998-2016.
Adolescent
Adult
Age Factors
Arm
Cross-Sectional Studies
Dermatitis, Allergic Contact
/ diagnosis
Dermatitis, Occupational
/ diagnosis
Female
Hand Dermatoses
/ chemically induced
Humans
Industry
/ statistics & numerical data
Male
Middle Aged
Nickel
/ toxicity
North America
/ epidemiology
Occupational Exposure
/ adverse effects
Occupations
/ statistics & numerical data
Patch Tests
Retrospective Studies
Sex Factors
Young Adult
Journal
Dermatitis : contact, atopic, occupational, drug
ISSN: 2162-5220
Titre abrégé: Dermatitis
Pays: United States
ID NLM: 101207335
Informations de publication
Date de publication:
Historique:
entrez:
17
9
2019
pubmed:
17
9
2019
medline:
23
2
2020
Statut:
ppublish
Résumé
The epidemiology of nickel allergy in occupational settings is not well understood. The aim of the study was to characterize occupationally related nickel allergy (ORNA). This is a retrospective cross-sectional analysis of 44,378 patients patch tested by the North American Contact Dermatitis Group from 1998 to 2016. Characteristics of individuals with ORNA were compared with those with non-ORNA (NORNA). A total of 7928 (18.2%) individuals were positive to nickel sulfate 2.5%. Two hundred sixty-eight (3.4%) had ORNA. As compared with NORNA, ORNA was statistically associated with the male sex (41.0% vs 12.9%, P < 0.001), a diagnosis of irritant contact dermatitis (22.4% vs 12.0%, P < 0.001), and no history of eczema (81.7% vs 75.7%, P = 0.0217). The most common sites of ORNA dermatitis were hand (39.9%) and arm (18.1%), which were significantly more common than in NORNA (P < 0.0001). Sixteen industry categories and 22 occupation categories were identified for ORNA; the most common industries were durable goods manufacturing (24.6%) and personal services (15.7%), and the most frequent occupations were hairdressers/cosmetologists/barbers (14.3%), machine operators (9.3%), and health care workers (7.1%). Overall 30% of ORNA occupations were in metalworking. Of 215 ORNA sources identified, instruments/phones/other equipment (16.3%), vehicles/machinery (15.8%), and tools (15.3%) were the most common. Occupational nickel allergy is distinct from nonoccupational nickel allergy.
Sections du résumé
BACKGROUND
BACKGROUND
The epidemiology of nickel allergy in occupational settings is not well understood.
OBJECTIVE
OBJECTIVE
The aim of the study was to characterize occupationally related nickel allergy (ORNA).
METHODS
METHODS
This is a retrospective cross-sectional analysis of 44,378 patients patch tested by the North American Contact Dermatitis Group from 1998 to 2016. Characteristics of individuals with ORNA were compared with those with non-ORNA (NORNA).
RESULTS
RESULTS
A total of 7928 (18.2%) individuals were positive to nickel sulfate 2.5%. Two hundred sixty-eight (3.4%) had ORNA. As compared with NORNA, ORNA was statistically associated with the male sex (41.0% vs 12.9%, P < 0.001), a diagnosis of irritant contact dermatitis (22.4% vs 12.0%, P < 0.001), and no history of eczema (81.7% vs 75.7%, P = 0.0217). The most common sites of ORNA dermatitis were hand (39.9%) and arm (18.1%), which were significantly more common than in NORNA (P < 0.0001). Sixteen industry categories and 22 occupation categories were identified for ORNA; the most common industries were durable goods manufacturing (24.6%) and personal services (15.7%), and the most frequent occupations were hairdressers/cosmetologists/barbers (14.3%), machine operators (9.3%), and health care workers (7.1%). Overall 30% of ORNA occupations were in metalworking. Of 215 ORNA sources identified, instruments/phones/other equipment (16.3%), vehicles/machinery (15.8%), and tools (15.3%) were the most common.
CONCLUSIONS
CONCLUSIONS
Occupational nickel allergy is distinct from nonoccupational nickel allergy.
Identifiants
pubmed: 31524759
doi: 10.1097/DER.0000000000000516
pii: 01206501-201909000-00005
doi:
Substances chimiques
Nickel
7OV03QG267
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM