Early necrotic skin lesions after a ABO-incompatible kidney transplantation: The threat of Cunninghamella Spp.
ABO Blood-Group System
/ immunology
Allografts
/ immunology
Blood Group Incompatibility
/ complications
Cunninghamella
/ immunology
Dermatomycoses
/ immunology
Fatal Outcome
Humans
Kidney
/ immunology
Kidney Transplantation
/ adverse effects
Living Donors
Male
Middle Aged
Mucormycosis
/ immunology
Necrosis
/ immunology
Skin
/ microbiology
Cunninghamella
ABO-incompatible kidney transplantation
mucormycosis
necrotic skin lesions
Journal
Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
07
04
2019
revised:
14
08
2019
accepted:
01
09
2019
pubmed:
19
9
2019
medline:
1
5
2020
entrez:
19
9
2019
Statut:
ppublish
Résumé
A 49-year-old man underwent ABO-incompatible kidney transplantation with a living donor. At day 33 post-transplantation, he presented with undiagnosed epilepsy with generalized tonic-clonic seizures. At day 44 post-transplantation, he developed left-sided pneumonia attributed to Aspergillus fumigatus and treatment with liposomal amphotericin B was initiated. At day 51 post-transplantation, necrotic skin lesions appeared. DNA sequencing in a fresh cutaneous biopsy finally identified Cunninghamella Spp., a member of the order Mucorales. Unfortunately, the necrotic lesions spread, and the patient died at day 60 post-transplantation. This case report highlights the infectious risk related to ABO-incompatible kidney transplantation and suggests a requirement for rapid identification of every skin lesion, even in the early phases of immunosuppression.
Substances chimiques
ABO Blood-Group System
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13173Informations de copyright
© 2019 Wiley Periodicals, Inc.
Références
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